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dc.creatorTomić, Ana
dc.creatorPetrović, Silvana
dc.creatorDrobac, Milica
dc.creatorTrajkovski, Bojana
dc.creatorMilenković, Marina
dc.creatorBožić, Dragana
dc.creatorNiketić, Marjan
dc.date.accessioned2019-09-02T11:18:41Z
dc.date.available2019-09-02T11:18:41Z
dc.date.issued2009
dc.identifier.issn1388-0209
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1273
dc.description.abstractThe methanol extracts of fruits and leaves of Athamanta turbith subsp. hungarica (Borbas) Tutin (Umbelliferae) and A. turbith subsp. haynaldii (Borbas & Uechtr.) Tutin were analyzed for their antimicrobial and antioxidant properties. Phenolic compounds (flavonoids and phenolic acids) of the extracts were examined using HPLC. All the extracts were characterized by the presence of caffeic acid derivates, luteolin and its glycosides, with luteolin 7-O-glucoside as one of the main compounds. Luteolin 7-O-rutinoside was detected only in A. turbith subsp. haynaldii extracts. Investigation of antimicrobial activity was performed against six bacteria and two fungal strains, using the agar diffusion technique and broth microdilution assay. The extracts of investigated A. turbith subspecies exerted similar antimicrobial activity, whereas the best activity was detected against Candida albicans. In order to investigate antioxidant properties, ferric ion reducing antioxidant power (FRAP), radical scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical (HO.), and the effect on lipid peroxidation (LP) were examined. All the examined extracts showed moderate antioxidant capacity, whereas the fruit extracts were more active than the extracts of leaves. Also, the extracts of A. turbith subsp. hungarica exerted higher antioxidant capacity than corresponding A. turbith subsp. haynaldii extracts. The relationship between estimated activity and chemical composition of the extracts is discussed.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/143012/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/143015/RS//
dc.rightsopenAccess
dc.sourcePharmaceutical Biology
dc.subjectAthamanta turbith subsp hungaricaen
dc.subjectAthamanta turbith subsp haynaldiien
dc.subjectantimicrobial activityen
dc.subjectantioxidant activityen
dc.subjectphenolic compoundsen
dc.titleAntimicrobial and antioxidant properties of methanol extracts of two Athamanta turbith subspeciesen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractТомић, Aна; Трајковски, Бојана; Петровић, Силвана; Миленковић, Марина; Божић, Драгана; Никетић, Марјан; Дробац, Милица;
dc.citation.volume47
dc.citation.issue4
dc.citation.spage314
dc.citation.epage319
dc.citation.other47(4): 314-319
dc.citation.rankM23
dc.identifier.wos000266630800009
dc.identifier.doi10.1080/13880200902748452
dc.identifier.scopus2-s2.0-77149155692
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/211/1271.pdf
dc.identifier.rcubconv_2153
dc.type.versionpublishedVersion


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