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dc.creatorMarković, Mirjana
dc.creatorIgnjatović, Svetlana
dc.creatorDajak, Marijana
dc.creatorMajkić-Singh, Nada
dc.date.accessioned2019-09-02T11:20:50Z
dc.date.available2019-09-02T11:20:50Z
dc.date.issued2010
dc.identifier.issn0038-4348
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1362
dc.description.abstractObjectives: The relevance of placental growth factor was analyzed at the admission of patients with acute coronary syndrome (ACS) without ST elevation in prognosis of fatal outcome after 30 days. Methods: We collected blood samples from 102 ACS patients admitted to the coronary unit with acute chest pain manifesting within the last 12 hours. Results: In all 102 admitted patients, higher values of placental growth factor (PLGF; >13.2 ng/L, average value) indicated a higher risk of fatal outcome (hazard ratio [HR] 2.28, 95% confidence interval [CI] 1.21-4.76, P = 0.0125). PLGF is an important independent prognostic marker (adjusted HR 2.35, 95% CI 1.98-4.61, P = 0.1338), and this was shown in a multiparameter model, which involved other statistically important markers of relative risk (age >65, gender, and estimated glomerular filtration rate [eGFR]). Conclusion: PLGF levels measured at 12 hours of symptom onset and 30 days later may independently predict fatal outcome in patients with ACS without ST elevation.en
dc.publisherLippincott Williams & Wilkins, Philadelphia
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/145010/RS//
dc.rightsrestrictedAccess
dc.sourceSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
dc.subject30 day outcomeen
dc.subjectnon-ST elevation myocardial infarctionen
dc.subjectplacental growth factoren
dc.titlePlacental Growth Factor as Short-Term Predicting Biomarker in Acute Coronary Syndrome Patients with Non-ST Elevation Myocardial Infarctionen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМајкић-Сингх, Нада; Марковић, Мирјана; Дајак, Маријана; Игњатовић, Светлана;
dc.citation.volume103
dc.citation.issue10
dc.citation.spage982
dc.citation.epage987
dc.citation.other103(10): 982-987
dc.citation.rankM22
dc.identifier.wos000282217900005
dc.identifier.doi10.1097/SMJ.0b013e3181eda4ef
dc.identifier.pmid20818309
dc.identifier.scopus2-s2.0-77958130426
dc.identifier.rcubconv_2355
dc.type.versionpublishedVersion


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