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Placental Growth Factor as Short-Term Predicting Biomarker in Acute Coronary Syndrome Patients with Non-ST Elevation Myocardial Infarction
dc.creator | Marković, Mirjana | |
dc.creator | Ignjatović, Svetlana | |
dc.creator | Dajak, Marijana | |
dc.creator | Majkić-Singh, Nada | |
dc.date.accessioned | 2019-09-02T11:20:50Z | |
dc.date.available | 2019-09-02T11:20:50Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 0038-4348 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/1362 | |
dc.description.abstract | Objectives: The relevance of placental growth factor was analyzed at the admission of patients with acute coronary syndrome (ACS) without ST elevation in prognosis of fatal outcome after 30 days. Methods: We collected blood samples from 102 ACS patients admitted to the coronary unit with acute chest pain manifesting within the last 12 hours. Results: In all 102 admitted patients, higher values of placental growth factor (PLGF; >13.2 ng/L, average value) indicated a higher risk of fatal outcome (hazard ratio [HR] 2.28, 95% confidence interval [CI] 1.21-4.76, P = 0.0125). PLGF is an important independent prognostic marker (adjusted HR 2.35, 95% CI 1.98-4.61, P = 0.1338), and this was shown in a multiparameter model, which involved other statistically important markers of relative risk (age >65, gender, and estimated glomerular filtration rate [eGFR]). Conclusion: PLGF levels measured at 12 hours of symptom onset and 30 days later may independently predict fatal outcome in patients with ACS without ST elevation. | en |
dc.publisher | Lippincott Williams & Wilkins, Philadelphia | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/145010/RS// | |
dc.rights | restrictedAccess | |
dc.source | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | |
dc.subject | 30 day outcome | en |
dc.subject | non-ST elevation myocardial infarction | en |
dc.subject | placental growth factor | en |
dc.title | Placental Growth Factor as Short-Term Predicting Biomarker in Acute Coronary Syndrome Patients with Non-ST Elevation Myocardial Infarction | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Мајкић-Сингх, Нада; Марковић, Мирјана; Дајак, Маријана; Игњатовић, Светлана; | |
dc.citation.volume | 103 | |
dc.citation.issue | 10 | |
dc.citation.spage | 982 | |
dc.citation.epage | 987 | |
dc.citation.other | 103(10): 982-987 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000282217900005 | |
dc.identifier.doi | 10.1097/SMJ.0b013e3181eda4ef | |
dc.identifier.pmid | 20818309 | |
dc.identifier.scopus | 2-s2.0-77958130426 | |
dc.type.version | publishedVersion |