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Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment

Authorized Users Only
2010
Authors
Vujović, Ana
Kotur-Stevuljević, Jelena
Kornić, D.
Spasojević-Kalimanovska, Vesna
Spasić, Slavica
Bogavac-Stanojević, Nataša
Stefanović, Aleksandra
Deanović, M.
Babka, Sofika
Aleksić, B.
Jelić-Ivanović, Zorana
Article (Published version)
Metadata
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Abstract
Objective: To evaluate the possible relationship between industrial air pollution and oxidative stress in schoolchildren by comparing parameters from children residing in two nearby localities with contrasting environmental conditions. Participants: 42 schoolchildren (12-15 years) from Pancevo (site of Serbia's largest petrochemical installation) formed the exposed group. 82 schoolchildren from Kovacica village, located 30 km north of Pancevo, formed the non-exposed group. Methods: Oxidative stress status, anti-oxidative defense parameters, paraoxonase-1 status, lipid status, glucose concentration and leukocyte counts were compared in two groups. Results: The children from Pancevo showed higher level of oxidative stress demonstrated by an elevated malondialdehyde concentration (P lt 0.001) and decreased superoxide dismutase activity (P lt 0.01) in comparison to the non-exposed group. Conclusions: The results suggested a relationship between the presence of air pollutants and increased... oxidative stress in schoolchildren residing in an industrial environment.

Keywords:
Air pollution / Anti-oxidative defense / Cardiovascular disease / Environment / Oxidative stress
Source:
Indian Pediatrics, 2010, 47, 3, 233-239
Publisher:
  • Indian Acad Pediatrics, New Delhi
Projects:
  • Ispitivanje biohemijskih i genetičkih faktora rizika kao uzročnika i markera ateroskleroze i drugih oboljenja: analitički i klinički aspekti (RS-145036)

DOI: 10.1007/s13312-010-0045-y

ISSN: 0019-6061

PubMed: 19578228

WoS: 000276011100006

Scopus: 2-s2.0-77949747704
[ Google Scholar ]
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11
URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/1377
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  • Radovi istraživača / Researchers’ publications
Institution
Pharmacy

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