The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.
TY - JOUR
AU - Popović, Višnja
AU - Petrović, Silvana
AU - Drobac, Milica
AU - Milenković, Marina
AU - Couladis, Maria
AU - Tzakou, Olga
AU - Duraki, Semija
AU - Niketić, Marjan
PY - 2010
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1385
AB - The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.
PB - Natural Products Inc, Westerville
T2 - Natural Product Communications
T1 - Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity
VL - 5
IS - 2
SP - 307
EP - 310
UR - https://hdl.handle.net/21.15107/rcub_farfar_1385
ER -
@article{
author = "Popović, Višnja and Petrović, Silvana and Drobac, Milica and Milenković, Marina and Couladis, Maria and Tzakou, Olga and Duraki, Semija and Niketić, Marjan",
year = "2010",
abstract = "The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity",
volume = "5",
number = "2",
pages = "307-310",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1385"
}
Popović, V., Petrović, S., Drobac, M., Milenković, M., Couladis, M., Tzakou, O., Duraki, S.,& Niketić, M.. (2010). Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity. in Natural Product Communications
Natural Products Inc, Westerville., 5(2), 307-310.
https://hdl.handle.net/21.15107/rcub_farfar_1385
Popović V, Petrović S, Drobac M, Milenković M, Couladis M, Tzakou O, Duraki S, Niketić M. Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity. in Natural Product Communications. 2010;5(2):307-310.
https://hdl.handle.net/21.15107/rcub_farfar_1385 .
Popović, Višnja, Petrović, Silvana, Drobac, Milica, Milenković, Marina, Couladis, Maria, Tzakou, Olga, Duraki, Semija, Niketić, Marjan, "Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity" in Natural Product Communications, 5, no. 2 (2010):307-310,
https://hdl.handle.net/21.15107/rcub_farfar_1385 .
