Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity
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Popović, VišnjaPetrović, Silvana

Drobac, Milica

Milenković, Marina

Couladis, Maria
Tzakou, Olga
Duraki, Semija
Niketić, Marjan

Article (Published version)

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The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.
Keywords:
Laserpitium zernyi / Apiaceae / Essential oil composition / alpha-bisabolol / Antimicrobial activitySource:
Natural Product Communications, 2010, 5, 2, 307-310Publisher:
- Natural Products Inc, Westerville
Funding / projects:
- Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija (RS-143012)
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PharmacyTY - JOUR AU - Popović, Višnja AU - Petrović, Silvana AU - Drobac, Milica AU - Milenković, Marina AU - Couladis, Maria AU - Tzakou, Olga AU - Duraki, Semija AU - Niketić, Marjan PY - 2010 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1385 AB - The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains. PB - Natural Products Inc, Westerville T2 - Natural Product Communications T1 - Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity VL - 5 IS - 2 SP - 307 EP - 310 UR - https://hdl.handle.net/21.15107/rcub_farfar_1385 ER -
@article{ author = "Popović, Višnja and Petrović, Silvana and Drobac, Milica and Milenković, Marina and Couladis, Maria and Tzakou, Olga and Duraki, Semija and Niketić, Marjan", year = "2010", abstract = "The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Grain (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.", publisher = "Natural Products Inc, Westerville", journal = "Natural Product Communications", title = "Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity", volume = "5", number = "2", pages = "307-310", url = "https://hdl.handle.net/21.15107/rcub_farfar_1385" }
Popović, V., Petrović, S., Drobac, M., Milenković, M., Couladis, M., Tzakou, O., Duraki, S.,& Niketić, M.. (2010). Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity. in Natural Product Communications Natural Products Inc, Westerville., 5(2), 307-310. https://hdl.handle.net/21.15107/rcub_farfar_1385
Popović V, Petrović S, Drobac M, Milenković M, Couladis M, Tzakou O, Duraki S, Niketić M. Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity. in Natural Product Communications. 2010;5(2):307-310. https://hdl.handle.net/21.15107/rcub_farfar_1385 .
Popović, Višnja, Petrović, Silvana, Drobac, Milica, Milenković, Marina, Couladis, Maria, Tzakou, Olga, Duraki, Semija, Niketić, Marjan, "Essential Oil from the Underground Parts of Laserpitium zernyi: Potential Source of alpha-Bisabolol and its Antimicrobial Activity" in Natural Product Communications, 5, no. 2 (2010):307-310, https://hdl.handle.net/21.15107/rcub_farfar_1385 .