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Anticoagulant effect of tungstophosphoric acid salt studied by IR spectroscopy

dc.creatorMioč, Ubavka B.
dc.creatorKuntić, Vesna
dc.creatorNedić, Zoran P.
dc.creatorFilipović, I.M
dc.creatorJelić, S.B
dc.date.accessioned2019-09-02T10:49:30Z
dc.date.available2019-09-02T10:49:30Z
dc.date.issued1996
dc.identifier.issn0352-5139
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/141
dc.description.abstractThe influence of the Li and Na salts of 12-tungstophosphoric acid H3P W12O40(WPA) was tested for in vitro effects on blood coagulation. It was found that only Li3WPA shows anticoagulant effects, but compared with WPA activity, the activity of Li salt is diminished. IR spectroscopy was used to define the reaction between these salts, and coagulation proteins. The appearance of bands characteristic of oxonium ion (H3O+) in the IR spectra indicates blocking of the active center of the protein through a very strong hydrogen bond.en
dc.publisherSrpsko hemijsko društvo, Beograd
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of the Serbian Chemical Society
dc.subjectAnticoagulant effecten
dc.subjectHydrogen bonden
dc.subjectIR spectraen
dc.subjectTungstophosphoric acid saltsen
dc.titleAnticoagulant effect of tungstophosphoric acid salt studied by IR spectroscopyen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractМиоч, Убавка Б.; Недић, Зоран П.; Кунтић, Весна; Филиповић, И.М; Јелић, С.Б;
dc.citation.volume61
dc.citation.issue9
dc.citation.spage767
dc.citation.epage771
dc.citation.other61(9): 767-771
dc.identifier.scopus2-s2.0-0030521327
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_141
dc.type.versionpublishedVersion


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