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dc.creatorJelić-Ivanović, Zorana
dc.creatorSpasojević-Kalimanovska, Vesna
dc.creatorStanković, B
dc.creatorTopić, Aleksandra
dc.creatorSpasić, S
dc.date.accessioned2019-09-02T10:49:34Z
dc.date.available2019-09-02T10:49:34Z
dc.date.issued1996
dc.identifier.issn0001-5652
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/143
dc.description.abstractThe distribution of PI (protease inhibitor) phenotypes and PI M subtypes was studied in 200 patients with monoclonal gammopathies and 320 healthy blood donors by isoelectric focusing in thin-layer polyacrylamide gels, pH range 4-5. The distribution of PI phenotypes and gene frequencies in the patients differed significantly from the corresponding values found in the blood donors, as shown by the chi(2) test (chi(2) = 16.5, p = 0.02 and chi(2) = 17.6, p = 0.0014, respectively). A lower frequency of the M3 variant was observed in patients, both in homozygous (PI M3) and heterozygous forms (PI M1M3 and PI M2M3). No significant difference between PIz allele frequencies in patients and healthy controls was found.en
dc.publisherKarger, Basel
dc.rightsrestrictedAccess
dc.sourceHuman Heredity
dc.titleLow frequency of PIM3 gene in patients with monoclonal gammopathiesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСпасић, С; Јелић-Ивановић, Зорана; Спасојевић-Калимановска, Весна; Станковић, Б; Топић, A;
dc.citation.volume46
dc.citation.issue2
dc.citation.spage115
dc.citation.epage117
dc.citation.other46(2): 115-117
dc.identifier.wosA1996TY47900009
dc.identifier.doi10.1159/000154337
dc.identifier.pmid8666412
dc.identifier.scopus2-s2.0-0029664902
dc.identifier.rcubconv_4438
dc.type.versionpublishedVersion


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