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Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts

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2011
Cytotoxicity_and_antimicrobial_pub_2011.pdf (142.2Kb)
Authors
Kundaković, Tatjana
Milenković, Marina
Topić, Aleksandra
Stanojković, Tatjana
Juranić, Zorica
Lakušić, Branislava
Article (Published version)
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Abstract
Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.
Keywords:
Teucrium scordium subsp scordioides / cytotoxicity / antimicrobial activity
Source:
African Journal of Microbiology Research, 2011, 5, 19, 2950-2954
Publisher:
  • Academic Journals, Victoria Island
Projects:
  • Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation (RS-173021)

ISSN: 1996-0808

WoS: 000298919700014

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URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/1489
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  • Radovi istraživača / Researchers’ publications
Institution
Pharmacy

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