Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.
TY - JOUR
AU - Kundaković, Tatjana
AU - Milenković, Marina
AU - Topić, Aleksandra
AU - Stanojković, Tatjana
AU - Juranić, Zorica
AU - Lakušić, Branislava
PY - 2011
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1489
AB - Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.
PB - Academic Journals, Victoria Island
T2 - African Journal of Microbiology Research
T1 - Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts
VL - 5
IS - 19
SP - 2950
EP - 2954
ER -
@article{
author = "Kundaković, Tatjana and Milenković, Marina and Topić, Aleksandra and Stanojković, Tatjana and Juranić, Zorica and Lakušić, Branislava",
year = "2011",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/1489",
abstract = "Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.",
publisher = "Academic Journals, Victoria Island",
journal = "African Journal of Microbiology Research",
title = "Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts",
volume = "5",
number = "19",
pages = "2950-2954"
}
Kundaković T, Milenković M, Topić A, Stanojković T, Juranić Z, Lakušić B. Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts. African Journal of Microbiology Research. 2011;5(19):2950-2954
Kundaković, T., Milenković, M., Topić, A., Stanojković, T., Juranić, Z.,& Lakušić, B. (2011). Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts.
African Journal of Microbiology ResearchAcademic Journals, Victoria Island., 5(19), 2950-2954.
Kundaković Tatjana, Milenković Marina, Topić Aleksandra, Stanojković Tatjana, Juranić Zorica, Lakušić Branislava, "Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts" 5, no. 19 (2011):2950-2954
