Cytotoxicity and antimicrobial activity of Teucrium scordium L. (Lamiaceae) extracts
Authors
Kundaković, Tatjana
Milenković, Marina

Topić, Aleksandra

Stanojković, Tatjana

Juranić, Zorica
Lakušić, Branislava

Article (Published version)

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Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane and methanol extracts of Teucrium scordium subspec. scordioides was studied. Cyclohexane and dichlormethane extracts of T. scordium possessed high citotoxicity against MDA-MB-361 cells (IC(50)=130.33+/-0.1 mu g/ml and IC(50)=189.89+/-3.99 mu g/ml, respectively). Dichlormethane extract was more effective against MDA-MB-453 cell line (IC(50)=130.33 +/- 0.1 mu g/ml). The methanol extract of T. scordium possessed no cytotoxicity against breast cancer cell lines, MDA-MB-361 and MDA-MB-453. Herb extracts of T. scordium have shown weak antibacterial activity on Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Bacillus subtilis with no activity against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, and Candida albicans.
Keywords:
Teucrium scordium subsp scordioides / cytotoxicity / antimicrobial activitySource:
African Journal of Microbiology Research, 2011, 5, 19, 2950-2954Publisher:
- Academic Journals, Victoria Island
Projects:
- Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation (RS-173021)