Приказ основних података о документу

dc.creatorSavić, Snežana
dc.creatorLukić, Milica
dc.creatorPantelić, Ivana
dc.creatorReichl, Stephan
dc.creatorTamburić, Slobodanka
dc.creatorMueller-Goymann, Christel
dc.date.accessioned2019-09-02T11:24:50Z
dc.date.available2019-09-02T11:24:50Z
dc.date.issued2011
dc.identifier.issn0021-9797
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/1533
dc.description.abstractTo be considered as a suitable vehicle for drugs/cosmetic actives, an emulsion system should have a number of desirable properties mainly dependent on surfactant used for its stabilization. In the current study, C12-14 alkyl polyglucoside (APG)-mixed emulsifier of natural origin has been investigated in a series of binary (emulsifier concentration 10-25% (w/w)) and ternary systems with fixed emulsifier content (15% (w/w)) with or without glycerol. To elucidate the systems' colloidal structure the following physicochemical techniques were employed: polarization and transmission electron microscopy, X-ray diffraction (WAXD and SAXD), thermal analysis (DSC and TGA), complex rheological, pH, and conductivity measurements. Additionally, the emulsion vehicles' skin hydration potential was tested in vivo, on human skin under occlusion. In a series of binary systems with fixed emulsifier/water ratios ranging from 10/90 to 25/75 the predominance of a lamellar mesophase was found, changing its character from a liquid crystalline to a gel crystalline type. The same was observed in gel emulsions containing equal amounts of emulsifier and oil (15% (w/w)), but varying in glycerol content (0-25%). Different emulsion samples exhibited different water distribution modes in the structure, reflecting their rheological behavior and also their skin hydration capacity.en
dc.publisherAcademic Press Inc Elsevier Science, San Diego
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34031/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Colloid and Interface Science
dc.subjectAlkyl polyglucoside-mixed emulsifieren
dc.subjectLamellar mesophaseen
dc.subjectWater distributionen
dc.subjectRheological behavioren
dc.subjectSkin hydrationen
dc.titleAn alkyl polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of colloidal structure on emulsions skin hydration potentialen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЛукић, Милица; Реицхл, Степхан; Пантелић, Ивана; Муеллер-Гоyманн, Цхристел; Савић, Снежана; Тамбурић, Слободанка;
dc.citation.volume358
dc.citation.issue1
dc.citation.spage182
dc.citation.epage191
dc.citation.other358(1): 182-191
dc.citation.rankM22
dc.identifier.wos000289600300025
dc.identifier.doi10.1016/j.jcis.2011.02.049
dc.identifier.pmid21421214
dc.identifier.scopus2-s2.0-79953300461
dc.type.versionpublishedVersion


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Приказ основних података о документу