FarFaR - Pharmacy Repository
University of Belgrade, Faculty of Pharmacy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction

No Thumbnail
Authors
Maksimović, Jelena
Kolar-Anić, Ljiljana
Anić, Slobodan
Ribić, Dragana D.
Pejić, Nataša
Article (Published version)
Metadata
Show full item record
Abstract
A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughpu...t of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.

Keywords:
pulse perturbations / Bray-Liebhafsky oscillatory reaction / kinetic determination / water-soluble B vitamins / pharmaceutical preparations
Source:
Journal of the Brazilian Chemical Society, 2011, 22, 1, 38-48
Publisher:
  • Soc Brasileira Quimica, Sao Paulo
Funding / projects:
  • Fizička hemija dinamičkih stanja i struktura neravnotežnih sistema - od monotone do oscilatorne evolucije i haosa (RS-142025)

ISSN: 0103-5053

WoS: 000285886500005

Scopus: 2-s2.0-78650927867
[ Google Scholar ]
13
12
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/1536
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Maksimović, Jelena
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
AU  - Ribić, Dragana D.
AU  - Pejić, Nataša
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1536
AB  - A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.
PB  - Soc Brasileira Quimica, Sao Paulo
T2  - Journal of the Brazilian Chemical Society
T1  - Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction
VL  - 22
IS  - 1
SP  - 38
EP  - 48
UR  - conv_2383
ER  - 
@article{
author = "Maksimović, Jelena and Kolar-Anić, Ljiljana and Anić, Slobodan and Ribić, Dragana D. and Pejić, Nataša",
year = "2011",
abstract = "A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.",
publisher = "Soc Brasileira Quimica, Sao Paulo",
journal = "Journal of the Brazilian Chemical Society",
title = "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction",
volume = "22",
number = "1",
pages = "38-48",
url = "conv_2383"
}
Maksimović, J., Kolar-Anić, L., Anić, S., Ribić, D. D.,& Pejić, N.. (2011). Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society
Soc Brasileira Quimica, Sao Paulo., 22(1), 38-48.
conv_2383
Maksimović J, Kolar-Anić L, Anić S, Ribić DD, Pejić N. Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society. 2011;22(1):38-48.
conv_2383 .
Maksimović, Jelena, Kolar-Anić, Ljiljana, Anić, Slobodan, Ribić, Dragana D., Pejić, Nataša, "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction" in Journal of the Brazilian Chemical Society, 22, no. 1 (2011):38-48,
conv_2383 .

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB