Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction
Апстракт
A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughpu...t of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.
Кључне речи:
pulse perturbations / Bray-Liebhafsky oscillatory reaction / kinetic determination / water-soluble B vitamins / pharmaceutical preparationsИзвор:
Journal of the Brazilian Chemical Society, 2011, 22, 1, 38-48Издавач:
- Soc Brasileira Quimica, Sao Paulo
Финансирање / пројекти:
- Физичка хемија динамичких стања и структура неравнотежних система - од монотоне до осцилаторне еволуције и хаоса (RS-MESTD-MPN2006-2010-142025)
Институција/група
PharmacyTY - JOUR AU - Maksimović, Jelena AU - Kolar-Anić, Ljiljana AU - Anić, Slobodan AU - Ribić, Dragana D. AU - Pejić, Nataša PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1536 AB - A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3. PB - Soc Brasileira Quimica, Sao Paulo T2 - Journal of the Brazilian Chemical Society T1 - Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction VL - 22 IS - 1 SP - 38 EP - 48 UR - https://hdl.handle.net/21.15107/rcub_farfar_1536 ER -
@article{ author = "Maksimović, Jelena and Kolar-Anić, Ljiljana and Anić, Slobodan and Ribić, Dragana D. and Pejić, Nataša", year = "2011", abstract = "A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.", publisher = "Soc Brasileira Quimica, Sao Paulo", journal = "Journal of the Brazilian Chemical Society", title = "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction", volume = "22", number = "1", pages = "38-48", url = "https://hdl.handle.net/21.15107/rcub_farfar_1536" }
Maksimović, J., Kolar-Anić, L., Anić, S., Ribić, D. D.,& Pejić, N.. (2011). Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society Soc Brasileira Quimica, Sao Paulo., 22(1), 38-48. https://hdl.handle.net/21.15107/rcub_farfar_1536
Maksimović J, Kolar-Anić L, Anić S, Ribić DD, Pejić N. Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society. 2011;22(1):38-48. https://hdl.handle.net/21.15107/rcub_farfar_1536 .
Maksimović, Jelena, Kolar-Anić, Ljiljana, Anić, Slobodan, Ribić, Dragana D., Pejić, Nataša, "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction" in Journal of the Brazilian Chemical Society, 22, no. 1 (2011):38-48, https://hdl.handle.net/21.15107/rcub_farfar_1536 .