The essential oils of Stachys spruneri Boiss. (sample A and sample B) were analyzed by GC and GC-MS. (+)-Isoabienol was the dominant component (49.5 and 48.2%, respectively of the total oils) among seventy-two identified constituents. Isoabienol was separated, purified by preparative thin-slayer chromatography, and further identified by means of physicochemical and spectrometric analysis. The microbial growth inhibitory properties of the essential oil and its main metabolite, the labdane diterpene isoabienol, were determined using the broth microdilution method against eight laboratory strains of bacteria (Gram- positive: Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, Bacillus subtilis, and Gram- negative: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and two strains of the yeast Candida albicans. Both essential oil and isoabienol showed considerable activity against all the microorganisms tested, with the isolated compound being mo...st active.
TY - JOUR
AU - Koutsaviti, Aikaterini
AU - Milenković, Marina
AU - Tzakou, Olga
PY - 2011
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1546
AB - The essential oils of Stachys spruneri Boiss. (sample A and sample B) were analyzed by GC and GC-MS. (+)-Isoabienol was the dominant component (49.5 and 48.2%, respectively of the total oils) among seventy-two identified constituents. Isoabienol was separated, purified by preparative thin-slayer chromatography, and further identified by means of physicochemical and spectrometric analysis. The microbial growth inhibitory properties of the essential oil and its main metabolite, the labdane diterpene isoabienol, were determined using the broth microdilution method against eight laboratory strains of bacteria (Gram- positive: Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, Bacillus subtilis, and Gram- negative: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and two strains of the yeast Candida albicans. Both essential oil and isoabienol showed considerable activity against all the microorganisms tested, with the isolated compound being most active.
PB - Natural Products Inc, Westerville
T2 - Natural Product Communications
T1 - Antimicrobial Activity of the Essential Oil of Greek Endemic Stachys spruneri and its Main Component, Isoabienol
VL - 6
IS - 2
SP - 277
EP - 280
UR - https://hdl.handle.net/21.15107/rcub_farfar_1546
ER -
@article{
author = "Koutsaviti, Aikaterini and Milenković, Marina and Tzakou, Olga",
year = "2011",
abstract = "The essential oils of Stachys spruneri Boiss. (sample A and sample B) were analyzed by GC and GC-MS. (+)-Isoabienol was the dominant component (49.5 and 48.2%, respectively of the total oils) among seventy-two identified constituents. Isoabienol was separated, purified by preparative thin-slayer chromatography, and further identified by means of physicochemical and spectrometric analysis. The microbial growth inhibitory properties of the essential oil and its main metabolite, the labdane diterpene isoabienol, were determined using the broth microdilution method against eight laboratory strains of bacteria (Gram- positive: Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis, Bacillus subtilis, and Gram- negative: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and two strains of the yeast Candida albicans. Both essential oil and isoabienol showed considerable activity against all the microorganisms tested, with the isolated compound being most active.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Antimicrobial Activity of the Essential Oil of Greek Endemic Stachys spruneri and its Main Component, Isoabienol",
volume = "6",
number = "2",
pages = "277-280",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1546"
}
Koutsaviti, A., Milenković, M.,& Tzakou, O.. (2011). Antimicrobial Activity of the Essential Oil of Greek Endemic Stachys spruneri and its Main Component, Isoabienol. in Natural Product Communications
Natural Products Inc, Westerville., 6(2), 277-280.
https://hdl.handle.net/21.15107/rcub_farfar_1546
Koutsaviti A, Milenković M, Tzakou O. Antimicrobial Activity of the Essential Oil of Greek Endemic Stachys spruneri and its Main Component, Isoabienol. in Natural Product Communications. 2011;6(2):277-280.
https://hdl.handle.net/21.15107/rcub_farfar_1546 .
Koutsaviti, Aikaterini, Milenković, Marina, Tzakou, Olga, "Antimicrobial Activity of the Essential Oil of Greek Endemic Stachys spruneri and its Main Component, Isoabienol" in Natural Product Communications, 6, no. 2 (2011):277-280,
https://hdl.handle.net/21.15107/rcub_farfar_1546 .
