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dc.creatorHusinec, Suren
dc.creatorSavić, Vladimir
dc.creatorSimić, Milena
dc.creatorTešević, Vele
dc.creatorVidović, Dragoslav
dc.date.accessioned2019-09-02T11:25:36Z
dc.date.available2019-09-02T11:25:36Z
dc.date.issued2011
dc.identifier.issn0040-4039
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1567
dc.description.abstractAnnulation processes of isoquinoline and p-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172009/RS//
dc.relationNTU (CBC)
dc.rightsrestrictedAccess
dc.sourceTetrahedron-Asymmetry
dc.subjectIsoquinolineen
dc.subjectAnnulationsen
dc.subject8-Oxoprotoberberine skeletonsen
dc.subjectSynthesisen
dc.titleAnnulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivativesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractХусинец, Сурен; Видовић, Драгослав; Тешевић, Веле; Симић, Милена; Савић, Владимир;
dc.citation.volume52
dc.citation.issue21
dc.citation.spage2733
dc.citation.epage2736
dc.citation.other52(21): 2733-2736
dc.citation.rankM22
dc.identifier.wos000290602100030
dc.identifier.doi10.1016/j.tetlet.2011.03.085
dc.identifier.scopus2-s2.0-79955483488
dc.identifier.rcubconv_2431
dc.type.versionpublishedVersion


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