Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates... that BuChE may be a predictor of diabetes.
TY - JOUR
AU - Stojanov, Marina
AU - Stefanović, Aleksandra
AU - Dzingalasević, Gordana
AU - Mandić-Radić, Slavka
AU - Prostran, Milica
PY - 2011
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1568
AB - Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates that BuChE may be a predictor of diabetes.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Clinical Biochemistry
T1 - Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors
VL - 44
IS - 8-9
SP - 623
EP - 626
DO - 10.1016/j.clinbiochem.2011.03.028
ER -
@article{
author = "Stojanov, Marina and Stefanović, Aleksandra and Dzingalasević, Gordana and Mandić-Radić, Slavka and Prostran, Milica",
year = "2011",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/1568",
abstract = "Objective: We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female. Design and methods: The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated. Results: Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p lt 0.05) and albumin (p lt 0.001) with BuChE activity increment in males. In females glucose and albumin (p lt 0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders. Conclusion: The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates that BuChE may be a predictor of diabetes.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Clinical Biochemistry",
title = "Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors",
volume = "44",
number = "8-9",
pages = "623-626",
doi = "10.1016/j.clinbiochem.2011.03.028"
}
Stojanov, M., Stefanović, A., Dzingalasević, G., Mandić-Radić, S.,& Prostran, M. (2011). Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors.
Clinical Biochemistry
Pergamon-Elsevier Science Ltd, Oxford., 44(8-9), 623-626.
https://doi.org/10.1016/j.clinbiochem.2011.03.028
Stojanov M, Stefanović A, Dzingalasević G, Mandić-Radić S, Prostran M. Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors. Clinical Biochemistry. 2011;44(8-9):623-626
Stojanov Marina, Stefanović Aleksandra, Dzingalasević Gordana, Mandić-Radić Slavka, Prostran Milica, "Butyrylcholinesterase activity in young men and women: Association with cardiovascular risk factors" Clinical Biochemistry, 44, no. 8-9 (2011):623-626,
https://doi.org/10.1016/j.clinbiochem.2011.03.028 .
