Chromosome instability in Alzheimer's disease
Апстракт
Alzheimer's disease (AD), as the most common form of dementia, has for many years attracted the attention of researchers around the world, primarily because of the problems of reliable diagnostic methods that could help in the early detection of this devastating disease. One of the important aspects of genetic research related to AD is the analysis of chromosome instability which includes: aneuploidies of different chromosomes, telomere shortening and the phenomenon of premature centromere division (PCD). The aim of this study was to describe specific biomarkers in different types of cells as potential parameters for the diagnosis of AD in order to promptly recognize pre-symptomatic stages and prevent the development of disease and/or slow down its progression.
Кључне речи:
Alzheimer's disease / chromosomes / aneuploidy / telomeres / centromereИзвор:
Archives of Biological Sciences, 2011, 63, 3, 603-608Издавач:
- Srpsko biološko društvo, Beograd, i dr.
Финансирање / пројекти:
- Аберације ћелијског циклуса и утицај оксидативног стреса на неуродегенеративне процесе и малигну трансформацију ћелије (RS-MESTD-Basic Research (BR or ON)-173034)
DOI: 10.2298/ABS1103603P
ISSN: 0354-4664
WoS: 000294400500011
Scopus: 2-s2.0-79961186473
Институција/група
PharmacyTY - JOUR AU - Potparević, Biljana AU - Živković, Lada AU - Plećaš-Solarović, Bosiljka AU - Bajić, Vladan PY - 2011 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1615 AB - Alzheimer's disease (AD), as the most common form of dementia, has for many years attracted the attention of researchers around the world, primarily because of the problems of reliable diagnostic methods that could help in the early detection of this devastating disease. One of the important aspects of genetic research related to AD is the analysis of chromosome instability which includes: aneuploidies of different chromosomes, telomere shortening and the phenomenon of premature centromere division (PCD). The aim of this study was to describe specific biomarkers in different types of cells as potential parameters for the diagnosis of AD in order to promptly recognize pre-symptomatic stages and prevent the development of disease and/or slow down its progression. PB - Srpsko biološko društvo, Beograd, i dr. T2 - Archives of Biological Sciences T1 - Chromosome instability in Alzheimer's disease VL - 63 IS - 3 SP - 603 EP - 608 DO - 10.2298/ABS1103603P ER -
@article{ author = "Potparević, Biljana and Živković, Lada and Plećaš-Solarović, Bosiljka and Bajić, Vladan", year = "2011", abstract = "Alzheimer's disease (AD), as the most common form of dementia, has for many years attracted the attention of researchers around the world, primarily because of the problems of reliable diagnostic methods that could help in the early detection of this devastating disease. One of the important aspects of genetic research related to AD is the analysis of chromosome instability which includes: aneuploidies of different chromosomes, telomere shortening and the phenomenon of premature centromere division (PCD). The aim of this study was to describe specific biomarkers in different types of cells as potential parameters for the diagnosis of AD in order to promptly recognize pre-symptomatic stages and prevent the development of disease and/or slow down its progression.", publisher = "Srpsko biološko društvo, Beograd, i dr.", journal = "Archives of Biological Sciences", title = "Chromosome instability in Alzheimer's disease", volume = "63", number = "3", pages = "603-608", doi = "10.2298/ABS1103603P" }
Potparević, B., Živković, L., Plećaš-Solarović, B.,& Bajić, V.. (2011). Chromosome instability in Alzheimer's disease. in Archives of Biological Sciences Srpsko biološko društvo, Beograd, i dr.., 63(3), 603-608. https://doi.org/10.2298/ABS1103603P
Potparević B, Živković L, Plećaš-Solarović B, Bajić V. Chromosome instability in Alzheimer's disease. in Archives of Biological Sciences. 2011;63(3):603-608. doi:10.2298/ABS1103603P .
Potparević, Biljana, Živković, Lada, Plećaš-Solarović, Bosiljka, Bajić, Vladan, "Chromosome instability in Alzheimer's disease" in Archives of Biological Sciences, 63, no. 3 (2011):603-608, https://doi.org/10.2298/ABS1103603P . .