Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of risk factors for atherosclerosis development in a cohort of 141 chronic renal disease patients. Kaplan-Meier survival analysis was implemented to assess risk of death. Results: Kaplan-Meier analysis (Log rank = 12.06, P = 0.0072) showed higher risk of death with increasing number of risk factors in haemodialysis patients. Conclusions: Malnutrition in combination with inflammation and oxidative stress is associated with higher mortality in patients on long-term haemodialysis.
TY - JOUR
AU - Kotur-Stevuljević, Jelena
AU - Simić-Ogrizović, Sanja
AU - Dopsaj, Violeta
AU - Stefanović, Aleksandra
AU - Vujović, Ana
AU - Ivanić-Corlomanović, Tatjana
AU - Spasić, Slavica
AU - Spasojević-Kalimanovska, Vesna
AU - Jelić-Ivanović, Zorana
PY - 2012
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1623
AB - Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of risk factors for atherosclerosis development in a cohort of 141 chronic renal disease patients. Kaplan-Meier survival analysis was implemented to assess risk of death. Results: Kaplan-Meier analysis (Log rank = 12.06, P = 0.0072) showed higher risk of death with increasing number of risk factors in haemodialysis patients. Conclusions: Malnutrition in combination with inflammation and oxidative stress is associated with higher mortality in patients on long-term haemodialysis.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Clinical Biochemistry
T1 - A hazardous link between malnutrition, inflammation and oxidative stress in renal patients
VL - 45
IS - 15
SP - 1202
EP - 1205
DO - 10.1016/j.clinbiochem.2012.04.021
ER -
@article{
author = "Kotur-Stevuljević, Jelena and Simić-Ogrizović, Sanja and Dopsaj, Violeta and Stefanović, Aleksandra and Vujović, Ana and Ivanić-Corlomanović, Tatjana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana",
year = "2012",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/1623",
abstract = "Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of risk factors for atherosclerosis development in a cohort of 141 chronic renal disease patients. Kaplan-Meier survival analysis was implemented to assess risk of death. Results: Kaplan-Meier analysis (Log rank = 12.06, P = 0.0072) showed higher risk of death with increasing number of risk factors in haemodialysis patients. Conclusions: Malnutrition in combination with inflammation and oxidative stress is associated with higher mortality in patients on long-term haemodialysis.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Clinical Biochemistry",
title = "A hazardous link between malnutrition, inflammation and oxidative stress in renal patients",
volume = "45",
number = "15",
pages = "1202-1205",
doi = "10.1016/j.clinbiochem.2012.04.021"
}
Kotur-Stevuljević J, Simić-Ogrizović S, Dopsaj V, Stefanović A, Vujović A, Ivanić-Corlomanović T, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z. A hazardous link between malnutrition, inflammation and oxidative stress in renal patients. Clinical Biochemistry. 2012;45(15):1202-1205
Kotur-Stevuljević, J., Simić-Ogrizović, S., Dopsaj, V., Stefanović, A., Vujović, A., Ivanić-Corlomanović, T., Spasić, S., Spasojević-Kalimanovska, V.,& Jelić-Ivanović, Z. (2012). A hazardous link between malnutrition, inflammation and oxidative stress in renal patients.
Clinical BiochemistryPergamon-Elsevier Science Ltd, Oxford., 45(15), 1202-1205.
https://doi.org/10.1016/j.clinbiochem.2012.04.021
Kotur-Stevuljević Jelena, Simić-Ogrizović Sanja, Dopsaj Violeta, Stefanović Aleksandra, Vujović Ana, Ivanić-Corlomanović Tatjana, Spasić Slavica, Spasojević-Kalimanovska Vesna, Jelić-Ivanović Zorana, "A hazardous link between malnutrition, inflammation and oxidative stress in renal patients" 45, no. 15 (2012):1202-1205,
https://doi.org/10.1016/j.clinbiochem.2012.04.021 .
