Show simple item record

dc.creatorPeco-Antić, Amira
dc.creatorParipović, Dušan
dc.creatorKotur-Stevuljević, Jelena
dc.creatorStefanović, Aleksandra
dc.creatorScekić, Gordana
dc.creatorMiloševski-Lomić, Gordana
dc.date.accessioned2019-09-02T11:27:06Z
dc.date.available2019-09-02T11:27:06Z
dc.date.issued2012
dc.identifier.issn0009-9120
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1625
dc.description.abstractObjective: The aim of the study was to investigate renal functional reserve (RFR) and to assess its relationship with serum cystatin C and blood pressure in children with apparently normal congenital solitary functioning kidney (SFK). Material and methods: RFR was obtained from the difference of endogenous creatinine clearance (CrCs) before and after a meat-free oral protein load (OPL) in the patients who were pre-treated with cimetidine. Serum cystatin C and urinary protein excretion were determined before and after OPL Results: Among 22 patients (13 boys), aged 9.5 +/- 4.3years, 72.7% had increased serum cystatin C, and 54.5% had decreased RFR. Following OPL, CrCs and urine creatinine increased, while serum creatinine and cystatin C remained unchanged. The multiple regression analysis demonstrated that cystatin C could predict more than 90% of RFR variability. Conclusion: Half of the patients with apparently normal SFK had decreased RFR. Serum cystatin C is one of the best predictors of RFR.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175079/RS//
dc.rightsrestrictedAccess
dc.sourceClinical Biochemistry
dc.subjectGlomerular hyperfiltrationen
dc.subjectUnilateral renal agenesisen
dc.subjectMulticystic dysplastic kidneyen
dc.subjectRenal functionen
dc.subjectCystatin Cen
dc.titleRenal functional reserve in children with apparently normal congenital solitary functioning kidneyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМилошевски-Ломић, Гордана; Котур-Стевуљевић, Јелена; Пецо-Aнтић, Aмира; Стефановић, Aлександра; Париповић, Душан; Сцекић, Гордана;
dc.citation.volume45
dc.citation.issue15
dc.citation.spage1173
dc.citation.epage1177
dc.citation.other45(15): 1173-1177
dc.citation.rankM21
dc.identifier.wos000309631000010
dc.identifier.doi10.1016/j.clinbiochem.2012.06.018
dc.identifier.pmid22732526
dc.identifier.scopus2-s2.0-84866290056
dc.identifier.rcubconv_2703
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record