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dc.creatorĆurčić, Marijana
dc.creatorJanković, Saša
dc.creatorJaćević, Vesna
dc.creatorStanković, Sanja
dc.creatorVučinić, Slavica
dc.creatorDurgo, Ksenija
dc.creatorBulat, Zorica
dc.creatorAntonijević, Biljana
dc.date.accessioned2019-09-02T11:27:07Z
dc.date.available2019-09-02T11:27:07Z
dc.date.issued2012
dc.identifier.issn0004-1254
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/1627
dc.description.abstractThe aim of this study was to see how a mixture of cadmium (Cd) and decabrominated diphenyl ether (BDE209) affect thyroid function, namely thyroid-stimulating hormone (TSH), thyroxin (T4), free thyroxin (FT4), triiodothyronin (T3), and free triiodothyronin (FT3) in Wistar rats (eight per group) receiving either a single substance or their combination by gavage for 28 days. Three groups were receiving Cd alone in the doses of 2.5 mg kg(-1), 7.5 mg kg(-1), or 15 mg kg(-1) b. w. a day, three groups were receiving BDE209 in the doses of 1000 mg kg(-1), 2000 mg kg(-1), or 4000 mg kg(-1) b. w. a day, while nine groups were receiving different mixtures of Cd and BDE209 in these doses (3x3 design). The results have indicated that the Cd+BDE209 mixtures more potently disrupt thyroid hormone homeostasis than would be expected from these chemicals alone.en
dc.publisherInst Medical Research & Occupational Health, Zagreb
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46009/RS//
dc.rightsopenAccess
dc.sourceArhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
dc.subjectBDE209en
dc.subjectCden
dc.subjectthyroid-stimulating hormoneen
dc.subjectthyroxinen
dc.subjecttriiodothyroninen
dc.titleCombined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in ratsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЈаћевић, Весна; Вучинић, Славица; Дурго, Ксенија; Булат, Зорица; Станковић, Сања; Aнтонијевић, Биљана; Јанковић, Саша; Ћурчић, Маријана;
dc.citation.volume63
dc.citation.issue3
dc.citation.spage255
dc.citation.epage262
dc.citation.other63(3): 255-262
dc.citation.rankM23
dc.identifier.wos000309641400002
dc.identifier.doi10.2478/10004-1254-63-2012-2179
dc.identifier.pmid23152375
dc.identifier.scopus2-s2.0-84875761723
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/470/1625.pdf
dc.type.versionpublishedVersion


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