Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy
Samo za registrovane korisnike
2012
Autori
Stefanović, AleksandraKotur-Stevuljević, Jelena
Vujović, Ana
Spasić, Slavica
Spasojević-Kalimanovska, Vesna
Jelić-Ivanović, Zorana
Martinović, Jelena
Ardalić, Daniela
Mandić-Marković, Vesna
Miković, Željko
Cerović, Nikola
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Background: Pregnancy is a stressful condition linked with altered lipid profile, increased oxidative stress and increased inflammation processes. The purpose of the present study was to determine the associations between those alterations with increased weight gain during pregnancy. Methods: The atherogenic index of plasma (AIP) and oxidative stress status parameters were determinated in 50 healthy and 172 pregnant women with non-complicated pregnancy. Pregnant women were divided in four groups according to body mass index (BMI) values (BMI quartiles). Results: Oxidative stress parameters were significantly lower in the control group compared with all the pregnant women quartiles. Unexpectedly, differences in oxidative stress parameters between BMI quartiles groups were not significant. The antioxidant defence parameters remained quite similar in the different BMI quartiles. Weight gain and paraoxonase-1 (PON1) activities were independently associated with increased AIP while weight g...ain and triglyceride concentration were found to be significant predictors of PON1 activities. Conclusions: The results of our current study indicate the association of maternal weight gain during pregnancy and altered lipid profile, elevated oxidative stress and changed antioxidative capacity of PON1. Taken together all these facts indicate possible increased risk of cardiovascular disease (CVD) development in later life if the weight gain during pregnancy is excessive.
Ključne reči:
atherogenic index of plasma / oxidative stress / paraoxonase-1 pregnancyIzvor:
Clinical Chemistry and Laboratory Medicine, 2012, 50, 11, 2019-2025Izdavač:
- Walter de Gruyter Gmbh, Berlin
Finansiranje / projekti:
- Interaktivna uloga dislipidemije, oksidativnog stresa i inflamacije u aterosklerozi i drugim bolestima: genetički i biohemijski markeri (RS-MESTD-Basic Research (BR or ON)-175035)
DOI: 10.1515/cclm-2012-0117
ISSN: 1434-6621
PubMed: 23093082
WoS: 000310695300022
Scopus: 2-s2.0-84872949637
Institucija/grupa
PharmacyTY - JOUR AU - Stefanović, Aleksandra AU - Kotur-Stevuljević, Jelena AU - Vujović, Ana AU - Spasić, Slavica AU - Spasojević-Kalimanovska, Vesna AU - Jelić-Ivanović, Zorana AU - Martinović, Jelena AU - Ardalić, Daniela AU - Mandić-Marković, Vesna AU - Miković, Željko AU - Cerović, Nikola PY - 2012 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1635 AB - Background: Pregnancy is a stressful condition linked with altered lipid profile, increased oxidative stress and increased inflammation processes. The purpose of the present study was to determine the associations between those alterations with increased weight gain during pregnancy. Methods: The atherogenic index of plasma (AIP) and oxidative stress status parameters were determinated in 50 healthy and 172 pregnant women with non-complicated pregnancy. Pregnant women were divided in four groups according to body mass index (BMI) values (BMI quartiles). Results: Oxidative stress parameters were significantly lower in the control group compared with all the pregnant women quartiles. Unexpectedly, differences in oxidative stress parameters between BMI quartiles groups were not significant. The antioxidant defence parameters remained quite similar in the different BMI quartiles. Weight gain and paraoxonase-1 (PON1) activities were independently associated with increased AIP while weight gain and triglyceride concentration were found to be significant predictors of PON1 activities. Conclusions: The results of our current study indicate the association of maternal weight gain during pregnancy and altered lipid profile, elevated oxidative stress and changed antioxidative capacity of PON1. Taken together all these facts indicate possible increased risk of cardiovascular disease (CVD) development in later life if the weight gain during pregnancy is excessive. PB - Walter de Gruyter Gmbh, Berlin T2 - Clinical Chemistry and Laboratory Medicine T1 - Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy VL - 50 IS - 11 SP - 2019 EP - 2025 DO - 10.1515/cclm-2012-0117 ER -
@article{ author = "Stefanović, Aleksandra and Kotur-Stevuljević, Jelena and Vujović, Ana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana and Martinović, Jelena and Ardalić, Daniela and Mandić-Marković, Vesna and Miković, Željko and Cerović, Nikola", year = "2012", abstract = "Background: Pregnancy is a stressful condition linked with altered lipid profile, increased oxidative stress and increased inflammation processes. The purpose of the present study was to determine the associations between those alterations with increased weight gain during pregnancy. Methods: The atherogenic index of plasma (AIP) and oxidative stress status parameters were determinated in 50 healthy and 172 pregnant women with non-complicated pregnancy. Pregnant women were divided in four groups according to body mass index (BMI) values (BMI quartiles). Results: Oxidative stress parameters were significantly lower in the control group compared with all the pregnant women quartiles. Unexpectedly, differences in oxidative stress parameters between BMI quartiles groups were not significant. The antioxidant defence parameters remained quite similar in the different BMI quartiles. Weight gain and paraoxonase-1 (PON1) activities were independently associated with increased AIP while weight gain and triglyceride concentration were found to be significant predictors of PON1 activities. Conclusions: The results of our current study indicate the association of maternal weight gain during pregnancy and altered lipid profile, elevated oxidative stress and changed antioxidative capacity of PON1. Taken together all these facts indicate possible increased risk of cardiovascular disease (CVD) development in later life if the weight gain during pregnancy is excessive.", publisher = "Walter de Gruyter Gmbh, Berlin", journal = "Clinical Chemistry and Laboratory Medicine", title = "Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy", volume = "50", number = "11", pages = "2019-2025", doi = "10.1515/cclm-2012-0117" }
Stefanović, A., Kotur-Stevuljević, J., Vujović, A., Spasić, S., Spasojević-Kalimanovska, V., Jelić-Ivanović, Z., Martinović, J., Ardalić, D., Mandić-Marković, V., Miković, Ž.,& Cerović, N.. (2012). Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy. in Clinical Chemistry and Laboratory Medicine Walter de Gruyter Gmbh, Berlin., 50(11), 2019-2025. https://doi.org/10.1515/cclm-2012-0117
Stefanović A, Kotur-Stevuljević J, Vujović A, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z, Martinović J, Ardalić D, Mandić-Marković V, Miković Ž, Cerović N. Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy. in Clinical Chemistry and Laboratory Medicine. 2012;50(11):2019-2025. doi:10.1515/cclm-2012-0117 .
Stefanović, Aleksandra, Kotur-Stevuljević, Jelena, Vujović, Ana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Martinović, Jelena, Ardalić, Daniela, Mandić-Marković, Vesna, Miković, Željko, Cerović, Nikola, "Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy" in Clinical Chemistry and Laboratory Medicine, 50, no. 11 (2012):2019-2025, https://doi.org/10.1515/cclm-2012-0117 . .