Characterization and evaluation of solid self-microemulsifying drug delivery systems with porous carriers as systems for improved carbamazepine release

Authorized Users Only
2012
Authors
Milović, Mladen
Đuriš, Jelena
Đekić, Ljiljana
Vasiljević, Dragana
Ibrić, Svetlana
Article (Published version)
Metadata
Show full item record
Abstract
The purpose of this study was to investigate solid self-microemulsifying drug delivery system (SSMEDDS), as potential delivery system for poorly water soluble drug carbamazepine (CBZ). Self-microemulsifying drug delivery system (SMEDDS) was formulated using the surfactant polyoxyethylene 20 sorbitan monooleate [Polysorbate 80] (S), the cosurfactant PEG-40 hydrogenated castor oil [Cremophor (R) RH40]
Keywords:
Solid self-microemulsifying drug delivery systems / Magnesium aluminometasilicate / Porous silica / Carbamazepine / Dissolution rate improvement
Source:
International Journal of Pharmaceutics, 2012, 436, 1-2, 58-65
Publisher:
  • Elsevier Science BV, Amsterdam
Projects:
  • Ministry of Education and Science, Republic of Serbia

DOI: 10.1016/j.ijpharm.2012.06.032

ISSN: 0378-5173

PubMed: 22721847

WoS: 000308597600006

Scopus: 2-s2.0-84865284761
[ Google Scholar ]
77
65
URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/1639
Collections
Institution
Pharmacy