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dc.creatorVladimirov, S
dc.creatorMarković, L
dc.creatorAgbaba, Danica
dc.creatorŽivanov-Stakić, Dobrila
dc.creatorBrborić, Jasmina
dc.date.accessioned2019-09-02T10:50:07Z
dc.date.available2019-09-02T10:50:07Z
dc.date.issued1997
dc.identifier.issn0352-5139
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/166
dc.description.abstractA specific and simple HPLC procedure was developed, su table for the determination of dindamycin hydrochloride monohydrate (CLHC) and clindamycin 2-dihydrogenphosphate (CLPH) in pharmaceutical formulations. Rp-HPLC analysis was performed with a LCD-Analytical Consta Metric 3000 system, equipped with a Spectro Monitor 3100 UV/VIS detector. Lincosamides assay procedures were carried out on a Supelcosil R LC-18-DB (250 × 4,6 mm, 5 μm particles) column in an acetonitrile-potassium dihydrogenphosphate buffer (0.1 M; pH 2.50) (225:775 v/v) as mobile phase. Column effluents were monitored at 206 nm for clindamycin. The calibration curves in concentration ranges from 200 to 1800 μg/ml were established for the investigated clindamycins. The HPLC method was applied for the determination of clindamycin in pharmaceutical formulations. The obtained results and statistical parameters for both the investigated clindamycins in pharmaceutical formulations, were satisfactory and ranged from 99.99% to 104.18% (R.S.D. was ranged from 0.79% to 0.99%).en
dc.publisherSrpsko hemijsko društvo, Beograd
dc.rightsopenAccess
dc.sourceJournal of the Serbian Chemical Society
dc.subjectClindamycinen
dc.subjectHPLC determinationen
dc.subjectPharmaceutical formulationsen
dc.titleHigh performance liquid chromatographic determination of clindamycin in pharmaceutical formulationsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractМарковић, Л; Владимиров, С; Aгбаба, Даница; Живанов-Стакић, Добрила; Брборић, Јасмина;
dc.citation.volume62
dc.citation.issue2
dc.citation.spage177
dc.citation.epage181
dc.citation.other62(2): 177-181
dc.identifier.scopus2-s2.0-0031522045
dc.identifier.rcubconv_5381
dc.type.versionpublishedVersion


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