Show simple item record

dc.creatorPoluga, Jasmina
dc.creatorDopsaj, Violeta
dc.creatorVeljković, Milena
dc.creatorMaksić, N.
dc.creatorStojaković, Sonja
dc.creatorDunjić, Radica
dc.creatorDakić, Zorica
dc.creatorPavlović, Milorad
dc.date.accessioned2019-09-02T11:28:28Z
dc.date.available2019-09-02T11:28:28Z
dc.date.issued2012
dc.identifier.issn0354-4664
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1682
dc.description.abstractIn malaria, blood concentrations of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-6, are increased. In a study which included 34 patients, TNF-alpha and IL-6 were examined in two phases, immediately after the admission of patients, and at the end of antimalarial therapy, when the parasitemia was negative. The results show a significant increase of TNF-alpha and IL-6 in the first phase, before the effects of antimalarial therapy. A very strong correlation between TNF-alpha and IL-6 is also confirmed, which suggests their coordinated production. Increased TNF-alpha values were correlated with an older age, the level of parasitemia, the number of platelets and leukocytes, elevated values of procalcitonin, D-dimer and lactate dehydrogenase, and lower values of serum iron and antithrombin. Increased values of IL-6 were correlated with the level of parasitemia, the number of platelets and leukocytes, and elevated values of D-dimer and lactates.en
dc.publisherSrpsko biološko društvo, Beograd, i dr.
dc.rightsopenAccess
dc.sourceArchives of Biological Sciences
dc.subjectMalariaen
dc.subjectcytokinesen
dc.subjectTNF-alphaen
dc.subjectIL-6en
dc.subjectparasitemiaen
dc.titleIncreased tumor necrosis factor alpha and interleukin-6 serum levels and their correlation with laboratory parameters in patients with imported Malariaen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractСтојаковић, Соња; Дуњић, Радица; Дакић, Зорица; Павловић, Милорад; Максић, Н.; Полуга, Јасмина; Вељковић, Милена; Допсај, Виолета;
dc.citation.volume64
dc.citation.issue4
dc.citation.spage1577
dc.citation.epage1583
dc.citation.other64(4): 1577-1583
dc.citation.rankM23
dc.identifier.wos000312046200041
dc.identifier.doi10.2298/ABS1204577P
dc.identifier.scopus2-s2.0-84867833149
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/507/1680.pdf
dc.identifier.rcubconv_2736
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record