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dc.creatorKundaković, Tatjana
dc.creatorMilenković, Marina
dc.creatorZlatković, Sasa
dc.creatorNikolić, Vesna D.
dc.creatorNikolić, Goran
dc.creatorBinić, Ivana
dc.date.accessioned2019-09-02T11:29:03Z
dc.date.available2019-09-02T11:29:03Z
dc.date.issued2012
dc.identifier.issn1021-7096
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1706
dc.description.abstractBackground: Venous ulcers (ulcus cruris venosum) are a common chronic disease that requires continuing treatment and significantly influences a patient's way of life. The therapeutic effects of the ointment Herbadermal on epithelialization and microbial flora of venous ulcers in 25 patients (10 men and 15 women) were tested over a 7-week period. The major components of the ointment are extracts of garlic, St. John's wort, and calendula. Material and Methods: The patients were over 18 years of age, with ulceration of the lower leg no longer than 2 months or recurrent ulceration during the last 6 months. The involved patients did not use any other phytomedicines or supportive therapies. Parameters were evaluated before the treatment and every 2 weeks during the period of 7 weeks. The total treatment response was evaluated on the basis of epithelialization, granulation, fibrin deposits, exudation, and edema. Results: The percentage of epithelialization was 99.1% after 7 weeks, without significant effects on the microbial flora. Conclusion: This combination of extracts can be recommended as topical treatment for wound healing because of its epithelizing, anti-erythematous, and anti-edematous properties.en
dc.publisherKarger, Basel
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34012/RS//
dc.rightsrestrictedAccess
dc.sourceForschende Komplementarmedizin
dc.subjectVenous leg ulcersen
dc.subjectOintmenten
dc.subjectAllium sativumen
dc.subjectHypericum perforatumen
dc.subjectCalendula officinalisen
dc.titleTreatment of Venous Ulcers with the Herbal-Based Ointment Herbadermal (R): A Prospective Non-Randomized Pilot Studyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБинић, Ивана; Николић, Весна Д.; Миленковић, Марина; Златковић, Саса; Кундаковић, Татјана; Николић, Горан;
dc.citation.volume19
dc.citation.issue1
dc.citation.spage26
dc.citation.epage30
dc.citation.other19(1): 26-30
dc.citation.rankM22
dc.identifier.wos000302383900005
dc.identifier.doi10.1159/000335786
dc.identifier.pmid22398923
dc.identifier.scopus2-s2.0-84858326479
dc.identifier.rcubconv_2615
dc.type.versionpublishedVersion


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