Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms
Само за регистроване кориснике
1997
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This paper describes a simple densitometric method for the determination of metroprolol tartrate in tablets and ampoules. After separation on silica gel GF254 plates, using acetone-methanol-triethylamine as the mobile phase for the tablets and acetone-triethylamine for ampoules, the chromatographic zones corresponding to the spots of metoprolol were scanned. Quantitation was performed using a computer-controlled Camag TLC scanner and applying five-point calibration with polynomial regression. The calibration function was established in the ranges 1-28 mu g for tablets and 1-9 mu g for ampoules. The results obtained are precise and reproducible, with recovery values of 99.1-99.4%.
Извор:
Journal of Pharmaceutical and Biomedical Analysis, 1997, 15, 5, 581-585Издавач:
- Pergamon-Elsevier Science Ltd, Oxford
DOI: 10.1016/S0731-7085(96)01857-2
ISSN: 0731-7085
PubMed: 9127269
WoS: A1997WU19000003
Scopus: 2-s2.0-0030934094
Институција/група
PharmacyTY - JOUR AU - Vujić, Zorica AU - Radulović, D AU - Agbaba, Danica PY - 1997 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/173 AB - This paper describes a simple densitometric method for the determination of metroprolol tartrate in tablets and ampoules. After separation on silica gel GF254 plates, using acetone-methanol-triethylamine as the mobile phase for the tablets and acetone-triethylamine for ampoules, the chromatographic zones corresponding to the spots of metoprolol were scanned. Quantitation was performed using a computer-controlled Camag TLC scanner and applying five-point calibration with polynomial regression. The calibration function was established in the ranges 1-28 mu g for tablets and 1-9 mu g for ampoules. The results obtained are precise and reproducible, with recovery values of 99.1-99.4%. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Journal of Pharmaceutical and Biomedical Analysis T1 - Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms VL - 15 IS - 5 SP - 581 EP - 585 DO - 10.1016/S0731-7085(96)01857-2 ER -
@article{ author = "Vujić, Zorica and Radulović, D and Agbaba, Danica", year = "1997", abstract = "This paper describes a simple densitometric method for the determination of metroprolol tartrate in tablets and ampoules. After separation on silica gel GF254 plates, using acetone-methanol-triethylamine as the mobile phase for the tablets and acetone-triethylamine for ampoules, the chromatographic zones corresponding to the spots of metoprolol were scanned. Quantitation was performed using a computer-controlled Camag TLC scanner and applying five-point calibration with polynomial regression. The calibration function was established in the ranges 1-28 mu g for tablets and 1-9 mu g for ampoules. The results obtained are precise and reproducible, with recovery values of 99.1-99.4%.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Journal of Pharmaceutical and Biomedical Analysis", title = "Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms", volume = "15", number = "5", pages = "581-585", doi = "10.1016/S0731-7085(96)01857-2" }
Vujić, Z., Radulović, D.,& Agbaba, D.. (1997). Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms. in Journal of Pharmaceutical and Biomedical Analysis Pergamon-Elsevier Science Ltd, Oxford., 15(5), 581-585. https://doi.org/10.1016/S0731-7085(96)01857-2
Vujić Z, Radulović D, Agbaba D. Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms. in Journal of Pharmaceutical and Biomedical Analysis. 1997;15(5):581-585. doi:10.1016/S0731-7085(96)01857-2 .
Vujić, Zorica, Radulović, D, Agbaba, Danica, "Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms" in Journal of Pharmaceutical and Biomedical Analysis, 15, no. 5 (1997):581-585, https://doi.org/10.1016/S0731-7085(96)01857-2 . .