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Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms
dc.creator | Vujić, Zorica | |
dc.creator | Radulović, D | |
dc.creator | Agbaba, Danica | |
dc.date.accessioned | 2019-09-02T10:50:19Z | |
dc.date.available | 2019-09-02T10:50:19Z | |
dc.date.issued | 1997 | |
dc.identifier.issn | 0731-7085 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/173 | |
dc.description.abstract | This paper describes a simple densitometric method for the determination of metroprolol tartrate in tablets and ampoules. After separation on silica gel GF254 plates, using acetone-methanol-triethylamine as the mobile phase for the tablets and acetone-triethylamine for ampoules, the chromatographic zones corresponding to the spots of metoprolol were scanned. Quantitation was performed using a computer-controlled Camag TLC scanner and applying five-point calibration with polynomial regression. The calibration function was established in the ranges 1-28 mu g for tablets and 1-9 mu g for ampoules. The results obtained are precise and reproducible, with recovery values of 99.1-99.4%. | en |
dc.publisher | Pergamon-Elsevier Science Ltd, Oxford | |
dc.rights | restrictedAccess | |
dc.source | Journal of Pharmaceutical and Biomedical Analysis | |
dc.title | Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Вујић, Зорица; Aгбаба, Даница; Радуловић, Д; | |
dc.citation.volume | 15 | |
dc.citation.issue | 5 | |
dc.citation.spage | 581 | |
dc.citation.epage | 585 | |
dc.citation.other | 15(5): 581-585 | |
dc.identifier.wos | A1997WU19000003 | |
dc.identifier.doi | 10.1016/S0731-7085(96)01857-2 | |
dc.identifier.pmid | 9127269 | |
dc.identifier.scopus | 2-s2.0-0030934094 | |
dc.type.version | publishedVersion |