Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus
Апстракт
The importance of the association of antiphospholipid antibodies (aPL Abs) with the features of type II diabetes mellitus has not yet been elucidated. The aim of this work was to investigate the association of aPL Abs with adiponectin and non-esterified fatty acids (NEFA) in type II diabetes mellitus patients without micro and/or macrovascular complications, and to analyze the differences between the male and female patients with regard to the abovementioned parameters. Male patients with type II diabetes mellitus showed a positive correlation between NEFA concentrations and anti-oxLDL antibodies (r = 0.334, p = 0.019). A weak, but statistically significant correlation between adiponectin concentrations and the IgM isotype of anti-annexin A5 antibodies was found in type II diabetes mellitus patients (r = 0.285, p = 0.011). The presence of a positive correlation between NEFA and anti-oxLDL antibodies might be useful in the detection of patients with premature atherosclerosis in type II ...diabetes mellitus patients without any micro and/or macrovascular complications among type II diabetes mellitus patients.
Кључне речи:
antiphospholipid antibodies / adiponectin / diabetes mellitus type IIИзвор:
Journal of Medical Biochemistry, 2012, 31, 3, 199-204Издавач:
- Društvo medicinskih biohemičara Srbije, Beograd i Versita
Финансирање / пројекти:
- Биомаркери оштећења и дисфункције органа (RS-175036)
DOI: 10.2478/v10011-012-0009-y
ISSN: 1452-8258
WoS: 000304767500005
Scopus: 2-s2.0-84861860611
Институција/група
PharmacyTY - JOUR AU - Becarević, Mirjana AU - Seferović, Jelena AU - Ignjatović, Svetlana AU - Singh, Sandra AU - Majkić-Singh, Nada PY - 2012 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1756 AB - The importance of the association of antiphospholipid antibodies (aPL Abs) with the features of type II diabetes mellitus has not yet been elucidated. The aim of this work was to investigate the association of aPL Abs with adiponectin and non-esterified fatty acids (NEFA) in type II diabetes mellitus patients without micro and/or macrovascular complications, and to analyze the differences between the male and female patients with regard to the abovementioned parameters. Male patients with type II diabetes mellitus showed a positive correlation between NEFA concentrations and anti-oxLDL antibodies (r = 0.334, p = 0.019). A weak, but statistically significant correlation between adiponectin concentrations and the IgM isotype of anti-annexin A5 antibodies was found in type II diabetes mellitus patients (r = 0.285, p = 0.011). The presence of a positive correlation between NEFA and anti-oxLDL antibodies might be useful in the detection of patients with premature atherosclerosis in type II diabetes mellitus patients without any micro and/or macrovascular complications among type II diabetes mellitus patients. PB - Društvo medicinskih biohemičara Srbije, Beograd i Versita T2 - Journal of Medical Biochemistry T1 - Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus VL - 31 IS - 3 SP - 199 EP - 204 DO - 10.2478/v10011-012-0009-y ER -
@article{ author = "Becarević, Mirjana and Seferović, Jelena and Ignjatović, Svetlana and Singh, Sandra and Majkić-Singh, Nada", year = "2012", abstract = "The importance of the association of antiphospholipid antibodies (aPL Abs) with the features of type II diabetes mellitus has not yet been elucidated. The aim of this work was to investigate the association of aPL Abs with adiponectin and non-esterified fatty acids (NEFA) in type II diabetes mellitus patients without micro and/or macrovascular complications, and to analyze the differences between the male and female patients with regard to the abovementioned parameters. Male patients with type II diabetes mellitus showed a positive correlation between NEFA concentrations and anti-oxLDL antibodies (r = 0.334, p = 0.019). A weak, but statistically significant correlation between adiponectin concentrations and the IgM isotype of anti-annexin A5 antibodies was found in type II diabetes mellitus patients (r = 0.285, p = 0.011). The presence of a positive correlation between NEFA and anti-oxLDL antibodies might be useful in the detection of patients with premature atherosclerosis in type II diabetes mellitus patients without any micro and/or macrovascular complications among type II diabetes mellitus patients.", publisher = "Društvo medicinskih biohemičara Srbije, Beograd i Versita", journal = "Journal of Medical Biochemistry", title = "Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus", volume = "31", number = "3", pages = "199-204", doi = "10.2478/v10011-012-0009-y" }
Becarević, M., Seferović, J., Ignjatović, S., Singh, S.,& Majkić-Singh, N.. (2012). Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus. in Journal of Medical Biochemistry Društvo medicinskih biohemičara Srbije, Beograd i Versita., 31(3), 199-204. https://doi.org/10.2478/v10011-012-0009-y
Becarević M, Seferović J, Ignjatović S, Singh S, Majkić-Singh N. Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus. in Journal of Medical Biochemistry. 2012;31(3):199-204. doi:10.2478/v10011-012-0009-y .
Becarević, Mirjana, Seferović, Jelena, Ignjatović, Svetlana, Singh, Sandra, Majkić-Singh, Nada, "Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus" in Journal of Medical Biochemistry, 31, no. 3 (2012):199-204, https://doi.org/10.2478/v10011-012-0009-y . .