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dc.creatorPejović, M.
dc.creatorBogavac-Stanojević, Nataša
dc.creatorPopović, D.
dc.creatorKavarić, Sreten
dc.creatorStojanov, Marina
dc.date.accessioned2019-09-02T11:30:22Z
dc.date.available2019-09-02T11:30:22Z
dc.date.issued2012
dc.identifier.issn1841-0987
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1759
dc.description.abstractContext. There is a lack of evidence On thyroid hormonal status and the prevalence of thyroid autoimmune diseases in Montenegro. Objective. In order to get an idea about that we performed thyroid function tests on ambulatory patients from different areas of Montenegro. Design. The study took place since November 2005 till March 2007 at the Clinical Center of Montenegro. Subjects and methods. The study included 277 subjects of both sexes, referred for serum thyroid-stimulating hormone (TSH), thyroxin (T4) and free thyroxin (FT4), thyroperoxidase antibody (TPOAb) and thyroglobulin antibody (TgAb). Also a multi-step statistical analysis of the biochemical data was performed. Results. An age-dependent increment in serum TSH was detected in both males (p = 0.001) and females (p = 0.034). In females significant changes of T4 with age were detected (p = 0.017), but not in males (p = 0.427). Neither in males nor in females changes in FT4 were found (p = 0.342 and p = 0.831, respectively). A univariate logistic model demonstrated an association between thyroid antibodies and TSH, indicating that TSH >= 7.15 mU/L. was a better predictor of TPOAb (p = 0.001) than of TgAb (p = 0.01) presence. A multivariate model adjusted for both age and gender gave similar results. The highest TSH increment (86%) was found in sera containing both antibodies, while 33% of antibodies negative persons had TSH above 7.16 mU/L. Conclusion. The results demonstrate high percentage of subclinical thyroiditis among the investigated subjects.en
dc.publisherEditura Acad Romane, Bucuresti
dc.rightsrestrictedAccess
dc.sourceActa Endocrinologica-Bucharest
dc.titleA pilot study of thyroid testing in Montenegroen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБогавац-Станојевић, Наташа; Поповић, Д.; Стојанов, Марина; Пејовић, М.; Каварић, Сретен;
dc.citation.volume8
dc.citation.issue2
dc.citation.spage309
dc.citation.epage319
dc.citation.other8(2): 309-319
dc.citation.rankM23
dc.identifier.wos000305258700016
dc.identifier.doi10.4183/aeb.2012.309
dc.identifier.scopus2-s2.0-84865220941
dc.identifier.rcubconv_2643
dc.type.versionpublishedVersion


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