High-performance liquid chromatographic assay of 8-hydroxyquinoline sulfate and its stability in immunobiological preparations
Authorized Users Only
Article (Published version)
MetadataShow full item record
Because of the ability of g-hydroxyquinoline sulfate (8-HQS) to irreversibly bind metals from rubber stoppers, the stability of 8-HQS in tuberculin solutions was investigated, For the determination of 8-HQS, a simple and sensitive reversed-phase HPLC method with detection at 240 nm was developed and validated. Rapid decreases in concentrations of 8-HQS were found in samples stored in original vials which were exposed to different temperatures and vial positions.
Source:Journal of Chromatography A, 1998, 798, 1-2, 173-177
- Elsevier Science BV, Amsterdam