Приказ основних података о документу

dc.creatorVladimirov, S
dc.creatorIvanisević, L
dc.creatorAgbaba, Danica
dc.creatorBrborić, Jasmina
dc.creatorŽivanov-Stakić, Dobrila
dc.date.accessioned2019-09-02T10:50:35Z
dc.date.available2019-09-02T10:50:35Z
dc.date.issued1998
dc.identifier.issn0352-5139
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/184
dc.description.abstractA simple HPLC procedure, suitable for the determination of sodium fusidate (SF) in dosage forms, was developed. The method involves using a UV detector (208 nm) in the presence of basic buffered media (pH 7.25) under reversed-phase conditions (Supelcosil(R) LC18(TM), 3 mu m particles). The linear regression between the concentration of SF and the peak area, y = -4.4566 + 8.9238x with a coefficient of correlation r = 0.9985, was confirmed for SF in the concentration range from 25 mu g/ml to 150 mu g/ml. The detection limit of SF was 12.5 mu g/ml. The HPLC method was applied for the determination of SF in dosage forms: Stanicid(R) coated tablets, Stanicid(R) ointment and Stanicid(R) sterile gauze dressing. The concentrations and statistical parameters of sodium fusidate for all the investigated dosage forms were satisfactory and ranged from 100.41 to 105.39% (the R. S. D. ranged from 1.51 to 2.75%).en
dc.publisherSrpsko hemijsko društvo, Beograd
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of the Serbian Chemical Society
dc.subjectDosage formsen
dc.subjectRaw materialen
dc.subjectRp-HPLCen
dc.subjectSodium fusidateen
dc.subjectUV-detectionen
dc.titleDetermination of sodium fusidate in dosage forms by high performance liquid chromatographyen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractAгбаба, Даница; Брборић, Јасмина; Владимиров, С; Живанов-Стакић, Добрила; Иванисевић, Л;
dc.citation.volume63
dc.citation.issue6
dc.citation.spage475
dc.citation.epage480
dc.citation.other63(6): 475-480
dc.identifier.wos000073978300009
dc.identifier.scopus2-s2.0-0039346902
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_184
dc.type.versionpublishedVersion


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