Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop
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2013
Authors
Marčetić, Mirjana
Božić, Dragana

Milenković, Marina

Malesević, Nevenka
Radulović, Siniša
Kovačević, Nada

Article (Published version)

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In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright
Keywords:
Cotinus coggygria / young shoots / antimicrobial activity / antioxidant activity / anti-inflammatory activitySource:
Phytotherapy Research, 2013, 27, 11, 1658-1663Publisher:
- Wiley-Blackwell, Hoboken
Funding / projects:
- Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation (RS-173021)
DOI: 10.1002/ptr.4919
ISSN: 0951-418X
PubMed: 23280933
WoS: 000328330500010
Scopus: 2-s2.0-84886256365
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PharmacyTY - JOUR AU - Marčetić, Mirjana AU - Božić, Dragana AU - Milenković, Marina AU - Malesević, Nevenka AU - Radulović, Siniša AU - Kovačević, Nada PY - 2013 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1913 AB - In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright PB - Wiley-Blackwell, Hoboken T2 - Phytotherapy Research T1 - Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop VL - 27 IS - 11 SP - 1658 EP - 1663 DO - 10.1002/ptr.4919 ER -
@article{ author = "Marčetić, Mirjana and Božić, Dragana and Milenković, Marina and Malesević, Nevenka and Radulović, Siniša and Kovačević, Nada", year = "2013", abstract = "In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright", publisher = "Wiley-Blackwell, Hoboken", journal = "Phytotherapy Research", title = "Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop", volume = "27", number = "11", pages = "1658-1663", doi = "10.1002/ptr.4919" }
Marčetić, M., Božić, D., Milenković, M., Malesević, N., Radulović, S.,& Kovačević, N.. (2013). Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop. in Phytotherapy Research Wiley-Blackwell, Hoboken., 27(11), 1658-1663. https://doi.org/10.1002/ptr.4919
Marčetić M, Božić D, Milenković M, Malesević N, Radulović S, Kovačević N. Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop. in Phytotherapy Research. 2013;27(11):1658-1663. doi:10.1002/ptr.4919 .
Marčetić, Mirjana, Božić, Dragana, Milenković, Marina, Malesević, Nevenka, Radulović, Siniša, Kovačević, Nada, "Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop" in Phytotherapy Research, 27, no. 11 (2013):1658-1663, https://doi.org/10.1002/ptr.4919 . .