In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright
TY - JOUR
AU - Marčetić, Mirjana
AU - Božić, Dragana
AU - Milenković, Marina
AU - Malesević, Nevenka
AU - Radulović, Siniša
AU - Kovačević, Nada
PY - 2013
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1913
AB - In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright
PB - Wiley-Blackwell, Hoboken
T2 - Phytotherapy Research
T1 - Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop
VL - 27
IS - 11
SP - 1658
EP - 1663
DO - 10.1002/ptr.4919
ER -
@article{
author = "Marčetić, Mirjana and Božić, Dragana and Milenković, Marina and Malesević, Nevenka and Radulović, Siniša and Kovačević, Nada",
year = "2013",
abstract = "In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Phytotherapy Research",
title = "Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop",
volume = "27",
number = "11",
pages = "1658-1663",
doi = "10.1002/ptr.4919"
}
Marčetić, M., Božić, D., Milenković, M., Malesević, N., Radulović, S.,& Kovačević, N.. (2013). Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop. in Phytotherapy Research
Wiley-Blackwell, Hoboken., 27(11), 1658-1663.
https://doi.org/10.1002/ptr.4919
Marčetić M, Božić D, Milenković M, Malesević N, Radulović S, Kovačević N. Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop. in Phytotherapy Research. 2013;27(11):1658-1663.
doi:10.1002/ptr.4919 .
Marčetić, Mirjana, Božić, Dragana, Milenković, Marina, Malesević, Nevenka, Radulović, Siniša, Kovačević, Nada, "Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop" in Phytotherapy Research, 27, no. 11 (2013):1658-1663,
https://doi.org/10.1002/ptr.4919 . .
