Antimicrobial, antioxidant and anti-inflammatory activity of young shoots of the smoke tree, Cotinus coggygria Scop
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2013
Authors
Marčetić, Mirjana
Božić, Dragana

Milenković, Marina

Malesević, Nevenka
Radulović, Siniša
Kovačević, Nada

Article (Published version)

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Show full item recordAbstract
In this study, we investigated the antimicrobial activity of the young shoots of the smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and the derived ethyl acetate fraction effectively inhibited the growth of Gram-positive and Gram-negative bacteria (MIC 25-200 mu g/ml), while the chloroform fraction showed pronounced activity against the yeast Candida albicans (MIC 3.12 mu g/ml). The ethyl acetate fraction exhibited a significant ferric-reducing ability (10.7mmol Fe2+/g extract), a very high DPPH radical scavenging activity (SC50=1.7 mu g/ml) and inhibition of lipid peroxidation (IC50=41.8 mu g/ml). High amounts of total phenolics (929.8mg/g), tannins (833.8mg/g) and flavonoids (35.5mg/g) were determined in the ethyl acetate fraction, which also exerted significant anti-inflammatory (76.7%) and cytotoxic effects (IC50=15.6 mu g/ml). Copyright
Keywords:
Cotinus coggygria / young shoots / antimicrobial activity / antioxidant activity / anti-inflammatory activitySource:
Phytotherapy Research, 2013, 27, 11, 1658-1663Publisher:
- Wiley-Blackwell, Hoboken
Projects:
- Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation (RS-173021)
DOI: 10.1002/ptr.4919
ISSN: 0951-418X
PubMed: 23280933