Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura
Nema prikaza
Autori
Đorđević, SofijaStanisavljević, Dragana
Ristić, Mihailo
Milenković, Marina
Veličković, Dragan
Stojičević, Saša S.
Zlatković, Branislav
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
This study examines the essential oil and the ethanol extract of Artemisia alba Turra herb, in terms of chemical composition, antioxidant and antimicrobial activities in order to select the active pharmacological isolate for making phytopreparation from the group of bitter aromatics and/or bitter liqueurs. Chemical composition of the essential oils and volatile fractions of the extract was determined by GC-FID/GC-MS and non-volatile fractions of the extract by HPLC. The content of total phenolics and flavonoids in the extracts was determined by Folin-Ciocalteu reagent and aluminum chloride, respectively. The antioxidant activity of isolates was tested by FRAP and DPPH tests and the antimicrobial by microdilution method. Major constituents in the essential oil were camphor, artemisia ketone and 1,8-cineole (23.7%, 15.2% and 14.1%, respectively), and in the volatile fraction of the extract, scopoletin (14.0%) and corymbolone (10.3%). The main components in non-volatile fraction of the ex...tract were kaempferol 3-O-(6 ''-O-malonylglucoside)- 7-O-rhamnoside, chlorogenic acid and rutin (16.1%, 11.4% and 9.5% respectively). The content of total phenolics in the extract, expressed as gallic acid was 77.18 mg/g and flavonoids, expressed as rutin 53.80 mg/g of dry extract. Extract exhibited stronger antioxidant activity than essential oil and better antimicrobial activity on a larger number of tested microorganisms.
Ključne reči:
Artemisia alba Turra / essential oil / extract / GC-MS / HPLC / antioxidant / antimicrobial activityIzvor:
Digest Journal of Nanomaterials and Biostructures, 2013, 8, 4, 1377-1388Izdavač:
- Inst Materials Physics, Bucharest
Finansiranje / projekti:
- Razvoj i primena novih i tradicionalnih tehnologija u proizvodnji konkurentnih prehrambenih proizvoda sa dodatom vrednošću za evropsko i svetsko tržište - Stvorimo bogatstvo iz bogatstva Srbije (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46001)
Institucija/grupa
PharmacyTY - JOUR AU - Đorđević, Sofija AU - Stanisavljević, Dragana AU - Ristić, Mihailo AU - Milenković, Marina AU - Veličković, Dragan AU - Stojičević, Saša S. AU - Zlatković, Branislav PY - 2013 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1914 AB - This study examines the essential oil and the ethanol extract of Artemisia alba Turra herb, in terms of chemical composition, antioxidant and antimicrobial activities in order to select the active pharmacological isolate for making phytopreparation from the group of bitter aromatics and/or bitter liqueurs. Chemical composition of the essential oils and volatile fractions of the extract was determined by GC-FID/GC-MS and non-volatile fractions of the extract by HPLC. The content of total phenolics and flavonoids in the extracts was determined by Folin-Ciocalteu reagent and aluminum chloride, respectively. The antioxidant activity of isolates was tested by FRAP and DPPH tests and the antimicrobial by microdilution method. Major constituents in the essential oil were camphor, artemisia ketone and 1,8-cineole (23.7%, 15.2% and 14.1%, respectively), and in the volatile fraction of the extract, scopoletin (14.0%) and corymbolone (10.3%). The main components in non-volatile fraction of the extract were kaempferol 3-O-(6 ''-O-malonylglucoside)- 7-O-rhamnoside, chlorogenic acid and rutin (16.1%, 11.4% and 9.5% respectively). The content of total phenolics in the extract, expressed as gallic acid was 77.18 mg/g and flavonoids, expressed as rutin 53.80 mg/g of dry extract. Extract exhibited stronger antioxidant activity than essential oil and better antimicrobial activity on a larger number of tested microorganisms. PB - Inst Materials Physics, Bucharest T2 - Digest Journal of Nanomaterials and Biostructures T1 - Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura VL - 8 IS - 4 SP - 1377 EP - 1388 UR - https://hdl.handle.net/21.15107/rcub_farfar_1914 ER -
@article{ author = "Đorđević, Sofija and Stanisavljević, Dragana and Ristić, Mihailo and Milenković, Marina and Veličković, Dragan and Stojičević, Saša S. and Zlatković, Branislav", year = "2013", abstract = "This study examines the essential oil and the ethanol extract of Artemisia alba Turra herb, in terms of chemical composition, antioxidant and antimicrobial activities in order to select the active pharmacological isolate for making phytopreparation from the group of bitter aromatics and/or bitter liqueurs. Chemical composition of the essential oils and volatile fractions of the extract was determined by GC-FID/GC-MS and non-volatile fractions of the extract by HPLC. The content of total phenolics and flavonoids in the extracts was determined by Folin-Ciocalteu reagent and aluminum chloride, respectively. The antioxidant activity of isolates was tested by FRAP and DPPH tests and the antimicrobial by microdilution method. Major constituents in the essential oil were camphor, artemisia ketone and 1,8-cineole (23.7%, 15.2% and 14.1%, respectively), and in the volatile fraction of the extract, scopoletin (14.0%) and corymbolone (10.3%). The main components in non-volatile fraction of the extract were kaempferol 3-O-(6 ''-O-malonylglucoside)- 7-O-rhamnoside, chlorogenic acid and rutin (16.1%, 11.4% and 9.5% respectively). The content of total phenolics in the extract, expressed as gallic acid was 77.18 mg/g and flavonoids, expressed as rutin 53.80 mg/g of dry extract. Extract exhibited stronger antioxidant activity than essential oil and better antimicrobial activity on a larger number of tested microorganisms.", publisher = "Inst Materials Physics, Bucharest", journal = "Digest Journal of Nanomaterials and Biostructures", title = "Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura", volume = "8", number = "4", pages = "1377-1388", url = "https://hdl.handle.net/21.15107/rcub_farfar_1914" }
Đorđević, S., Stanisavljević, D., Ristić, M., Milenković, M., Veličković, D., Stojičević, S. S.,& Zlatković, B.. (2013). Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura. in Digest Journal of Nanomaterials and Biostructures Inst Materials Physics, Bucharest., 8(4), 1377-1388. https://hdl.handle.net/21.15107/rcub_farfar_1914
Đorđević S, Stanisavljević D, Ristić M, Milenković M, Veličković D, Stojičević SS, Zlatković B. Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura. in Digest Journal of Nanomaterials and Biostructures. 2013;8(4):1377-1388. https://hdl.handle.net/21.15107/rcub_farfar_1914 .
Đorđević, Sofija, Stanisavljević, Dragana, Ristić, Mihailo, Milenković, Marina, Veličković, Dragan, Stojičević, Saša S., Zlatković, Branislav, "Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba tura" in Digest Journal of Nanomaterials and Biostructures, 8, no. 4 (2013):1377-1388, https://hdl.handle.net/21.15107/rcub_farfar_1914 .