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dc.creatorĐorđević, Sofija
dc.creatorStanisavljević, Dragana
dc.creatorRistić, Mihailo
dc.creatorMilenković, Marina
dc.creatorVeličković, Dragan
dc.creatorStojičević, Saša S.
dc.creatorZlatković, Branislav
dc.date.accessioned2019-09-02T11:34:09Z
dc.date.available2019-09-02T11:34:09Z
dc.date.issued2013
dc.identifier.issn1842-3582
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1914
dc.description.abstractThis study examines the essential oil and the ethanol extract of Artemisia alba Turra herb, in terms of chemical composition, antioxidant and antimicrobial activities in order to select the active pharmacological isolate for making phytopreparation from the group of bitter aromatics and/or bitter liqueurs. Chemical composition of the essential oils and volatile fractions of the extract was determined by GC-FID/GC-MS and non-volatile fractions of the extract by HPLC. The content of total phenolics and flavonoids in the extracts was determined by Folin-Ciocalteu reagent and aluminum chloride, respectively. The antioxidant activity of isolates was tested by FRAP and DPPH tests and the antimicrobial by microdilution method. Major constituents in the essential oil were camphor, artemisia ketone and 1,8-cineole (23.7%, 15.2% and 14.1%, respectively), and in the volatile fraction of the extract, scopoletin (14.0%) and corymbolone (10.3%). The main components in non-volatile fraction of the extract were kaempferol 3-O-(6 ''-O-malonylglucoside)- 7-O-rhamnoside, chlorogenic acid and rutin (16.1%, 11.4% and 9.5% respectively). The content of total phenolics in the extract, expressed as gallic acid was 77.18 mg/g and flavonoids, expressed as rutin 53.80 mg/g of dry extract. Extract exhibited stronger antioxidant activity than essential oil and better antimicrobial activity on a larger number of tested microorganisms.en
dc.publisherInst Materials Physics, Bucharest
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS//
dc.rightsrestrictedAccess
dc.sourceDigest Journal of Nanomaterials and Biostructures
dc.subjectArtemisia alba Turraen
dc.subjectessential oilen
dc.subjectextracten
dc.subjectGC-MSen
dc.subjectHPLCen
dc.subjectantioxidanten
dc.subjectantimicrobial activityen
dc.titleChemical, antioxidant and antimicrobial analysis of the essential oil and extract of artemisia alba turaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЗлатковић, Бранислав; Ристић, Михаило; Величковић, Драган; Ђорђевић, Софија; Стојичевић, Саша С.; Станисављевић, Драгана; Миленковић, Марина;
dc.citation.volume8
dc.citation.issue4
dc.citation.spage1377
dc.citation.epage1388
dc.citation.other8(4): 1377-1388
dc.citation.rankM22
dc.identifier.wos000327818000004
dc.identifier.rcubconv_2969
dc.type.versionpublishedVersion


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