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dc.creatorJelić-Ivanović, Zorana
dc.creatorSpasić, S
dc.creatorSpasojević-Kalimanovska, Vesna
dc.date.accessioned2019-09-02T10:50:46Z
dc.date.available2019-09-02T10:50:46Z
dc.date.issued1998
dc.identifier.issn0354-3447
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/191
dc.description.abstractClinical accuracy of a laboratory test refers its ability to differentiate alternative states of healths, i.e, to classify patients into clinicaly relevant groups. Basic parameters and methods used for the assessment of clinical accuracy are the following: specificity, sensitivity, ROC-curve, predictive values and diagnostic efficiency. Sensitivity and specificity are inherent characteristics of laboratory tests, which are not influenced by the prevalence of target disease. ROC-curve, which is a sensitivity/specificity pair for different cut-off limits in the whole range of the obtained values, offers the best insight into the clinical performance of a laboratory test. The use of ROC-curve is the best way to compare clinical accuracies of different tests and to identify the cutoff limits that yield optimal test sensitivity and specificity. Predictive values are influenced by the disease prevalence, and are used mostly for interpretation of results or in building sequential diagnostic strategies. Diagnostic efficiency is a combined parameter which is easy to obtain, but is not very useful for the assessment of clinical accuracy.en
dc.publisherDruštvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
dc.rightsrestrictedAccess
dc.sourceJugoslovenska medicinska biohemija
dc.subjectClinical accuracyen
dc.subjectInterpretation of resultsen
dc.subjectPredictive valuesen
dc.subjectROC-curveen
dc.titleClinical value of laboratory measurementsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЈелић-Ивановић, Зорана; Спасић, С; Спасојевић-Калимановска, Весна;
dc.citation.volume17
dc.citation.issue4
dc.citation.spage367
dc.citation.epage375
dc.citation.other17(4): 367-375
dc.citation.rankM23
dc.identifier.wos000077903200001
dc.identifier.scopus2-s2.0-0032407310
dc.identifier.rcubconv_1175
dc.type.versionpublishedVersion


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