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dc.creatorBecarević, Mirjana
dc.creatorIgnjatović, Svetlana
dc.creatorMajkić-Singh, Nada
dc.date.accessioned2019-09-02T11:34:43Z
dc.date.available2019-09-02T11:34:43Z
dc.date.issued2013
dc.identifier.issn1452-8258
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/1934
dc.description.abstractIt has been proposed that apoptosis is one of the mechanisms involved in the generation of antiphospholipid antibodies. The presence of antiphospholipid antibodies is the main laboratory criterion for a definite diagnosis of the antiphospholipid syndrome. Annexinopathies are disorders characterized by deregulation of annexins expression levels and function. Annexin A5 has been used as an agent for molecular imaging techniques (visualization of phosphatidylserine-expressing apoptotic cells) in vitro and in vivo in animal models and in patients (injection of human recombinant anxA5 into the patient's circulation). Although the determination of titers of anti-annexin A5 antibodies is not mandatory for the diagnosis of the antiphospholipid syndrome, it was reported that patients with primary antiphospholipid syndrome with a history of recurrent abortions had elevated titers of anti-annexin A5 antibodies, while the presence of thromboses was not associated with elevated levels of these antibodies.en
dc.publisherDruštvo medicinskih biohemičara Srbije, Beograd i Versita
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175036/RS//
dc.rightsopenAccess
dc.sourceJournal of Medical Biochemistry
dc.subjectapoptosisen
dc.subjectannexin A5en
dc.subjectanti-annexin A5 antibodiesen
dc.subjectantiphospholipid syndromeen
dc.titleApoptosis, annexin a5 and anti-Annexin a5 antibodies in the antiphospholipid syndromeen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМајкић-Сингх, Нада; Бецаревић, Мирјана; Игњатовић, Светлана;
dc.citation.volume32
dc.citation.issue2
dc.citation.spage89
dc.citation.epage95
dc.citation.other32(2): 89-95
dc.citation.rankM23
dc.identifier.wos000317253000001
dc.identifier.doi10.2478/jomb-2013-0014
dc.identifier.scopus2-s2.0-84881525810
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/707/1932.pdf
dc.type.versionpublishedVersion


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