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Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system
dc.creator | Pejić, Nataša | |
dc.creator | Sarap, Nataša B. | |
dc.creator | Maksimović, Jelena | |
dc.creator | Anić, Slobodan | |
dc.creator | Kolar-Anić, Ljiljana | |
dc.date.accessioned | 2019-09-02T11:34:50Z | |
dc.date.available | 2019-09-02T11:34:50Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1895-1066 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/1940 | |
dc.description.abstract | A simple and reliable novel kinetic method for the determination of piroxicam (PX) was proposed and validated. For quantitative determination of PX, the Bray-Liebhafsky (BL) oscillatory reaction was used in a stable non-equilibrium stationary state close to the bifurcation point. Under the optimized reaction conditions (T = 55.0A degrees C, [H2SO4](0) = 7.60x10(-2) mol L-1, [KIO3](0) = 5.90x10(-2) mol L-1, [H2O2](0) = 1.50x10(-1) mol L-1 and j (0) = 2.95x10(-2) min(-1)), the linear relationship between maximal potential shift Delta E (m) , and PX concentration was obtained in the concentration range 11.2-480.5 A mu g mL(-1) with a detection limit of 9.9 A mu g mL(-1). The method had a rather good sample throughput of 25 samples h(-1) with a precision RSD = 4.7% as well as recoveries RCV a parts per thousand currency sign 104.4%. Applicability of the proposed method to the direct determination of piroxicam in different pharmaceutical formulations (tablets, ampoules and gel) was demonstrated. | en |
dc.publisher | Versita, Warsaw | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172015/RS// | |
dc.rights | openAccess | |
dc.source | Central European Journal of Chemistry | |
dc.subject | Piroxicam | en |
dc.subject | Perturbation technique | en |
dc.subject | Bray-Liebhafsky oscillatory reaction | en |
dc.subject | Pharmaceutical preparations | en |
dc.title | Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Aнић, Слободан; Колар-Aнић, Љиљана; Максимовић, Јелена; Сарап, Наташа Б.; Пејић, Наташа; | |
dc.citation.volume | 11 | |
dc.citation.issue | 2 | |
dc.citation.spage | 180 | |
dc.citation.epage | 188 | |
dc.citation.other | 11(2): 180-188 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000311778700008 | |
dc.identifier.doi | 10.2478/s11532-012-0146-7 | |
dc.identifier.scopus | 2-s2.0-84875741601 | |
dc.identifier.fulltext | https://farfar.pharmacy.bg.ac.rs//bitstream/id/712/1938.pdf | |
dc.type.version | publishedVersion |