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dc.creatorPejcić, Tomislav P.
dc.creatorTulić, Cane
dc.creatorLalić, Nataša V.
dc.creatorGlisić, Biljana D.
dc.creatorIgnjatović, Svetlana
dc.creatorMarković, Biljana
dc.creatorHadzi-Đokić, Jovan B.
dc.date.accessioned2019-09-02T11:35:49Z
dc.date.available2019-09-02T11:35:49Z
dc.date.issued2013
dc.identifier.issn1195-9479
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/1978
dc.description.abstractPEJCIC TP, TULIC CD, LALIC NV, GLISIC BD, IGNJATOVIC SD, MARKOVIC BB, HADZI-DJOKK JB. Urinary prostate-specific antigen: predictor of benign prostatic hyperplasia progression? Can J Urol 2013;20(2):6707-6713. Introduction: Urinary prostate-specific antigen (uPSA) can be used as additional parameter of benign prostatic hyperplasia (BPH) progression. Materials and methods: From January 2001 to December 2011, uPSA was determined in 265 patients with benign prostate. Based on total prostate volume (TPV), the patients with benign prostate were divided in two groups: TPV lt 31 mL and TPV >= 31 mL. Additional three groups were formed upon MTOPS study criteria: non-progressive BPH group (TPV lt 31 mL, PSA lt 1.6 ng/mL, age lt 62 yrs), intermediate group (one, or two parameters {TPV, PSA, age} increased) and progressive BPH group (TPV >= 31 ml, PSA >= 1.6 ng/mL, age >= 62 yrs). Results: Average uPSA values in the groups TPV lt 31 mL and TPV 31 mL were 119.3 +/- 124.5 and 255.5 +/- 204.9 ng/mL, respectively and they were significantly different (p lt 0.0001). Average uPSA values in the non-progressive BPH group, intermediate group and progressive BPH group were 86.8 +/- 82.4 ng/mL, 166.6 +/- 164.9 ng/mL and 274.9 +/- 208.3 ng/mL, respectively and they were significantly different (p lt 0.0001). The level of uPSA correlated significantly with TPV (r = 0.32, p lt 0.0001). The cut off uPSA level of 150 ng/mL discriminates the patients with non-progressive BPH and progressive BPH with specificity of 0.83 and sensitivity of 0.67. Conclusion: The level of uPSA reflects prostatic hormonal activity and correlates with TPV, PSA and age. UPSA level >= 150 ng/mL can be used as additional predictive parameter of BPH progression.en
dc.publisherCanadian J Urology, St Laurent
dc.rightsrestrictedAccess
dc.sourceCanadian Journal of Urology
dc.subjectbenign prostatic hyperplasiaen
dc.subjectprostate-specific antigenen
dc.subjecturinary prostate specific antigenen
dc.titleUrinary prostate-specific antigen: predictor of benign prostatic hyperplasia progression?en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractХадзи-Ђокић, Јован Б.; Игњатовић, Светлана; Марковић, Биљана; Пејцић, Томислав П.; Тулић, Цане; Лалић, Наташа В.; Глисић, Биљана Д.;
dc.citation.volume20
dc.citation.issue2
dc.citation.spage6707
dc.citation.epage6713
dc.citation.other20(2): 6707-6713
dc.citation.rankM23
dc.identifier.wos000317811000007
dc.identifier.pmid23587511
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_1978
dc.type.versionpublishedVersion


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