Cyclodextrins are oligosaccharides which have recently been recognized as useful pharmaceutical excipients. The objective of this review is to summarized recent findings and applications of both unmodified and modified cyclodextrins for drug delivery. Its ability to form inclusion complexes with many drugs, were explored for designing of a particular drug carrier system. Cyclodextrin inclusion complexes demonstrate great potential against improvement of solubility, stability, dissolution rate, enhancement through biological membrane, etc. Furthermore, its safety profiles, via a variety of administration routes (oral, parenteral, transmucosal) are addressed. Finally, this paper is primarily focused on the findings related to the effects of cyclodextrins/anticancer drugs and cyclodextrins/prostaglandins delivery systems, and on the therapeutical potentiality of drugs.
Keywords:
Antineoplastic agents / Biotransformation / Cyclodextrins / Drug delivery systems / Prostaglandins
TY - JOUR
AU - Tasić, Ljiljana
AU - Milić, Jela
AU - Stupar, Mirjana
PY - 1998
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/198
AB - Cyclodextrins are oligosaccharides which have recently been recognized as useful pharmaceutical excipients. The objective of this review is to summarized recent findings and applications of both unmodified and modified cyclodextrins for drug delivery. Its ability to form inclusion complexes with many drugs, were explored for designing of a particular drug carrier system. Cyclodextrin inclusion complexes demonstrate great potential against improvement of solubility, stability, dissolution rate, enhancement through biological membrane, etc. Furthermore, its safety profiles, via a variety of administration routes (oral, parenteral, transmucosal) are addressed. Finally, this paper is primarily focused on the findings related to the effects of cyclodextrins/anticancer drugs and cyclodextrins/prostaglandins delivery systems, and on the therapeutical potentiality of drugs.
PB - Institut za onkologiju, Sremska Kamenica
T2 - Archive of Oncology
T1 - Cyclodextrins: New materials for drug disposition
VL - 6
IS - 3
SP - 125
EP - 129
UR - https://hdl.handle.net/21.15107/rcub_farfar_198
ER -
@article{
author = "Tasić, Ljiljana and Milić, Jela and Stupar, Mirjana",
year = "1998",
abstract = "Cyclodextrins are oligosaccharides which have recently been recognized as useful pharmaceutical excipients. The objective of this review is to summarized recent findings and applications of both unmodified and modified cyclodextrins for drug delivery. Its ability to form inclusion complexes with many drugs, were explored for designing of a particular drug carrier system. Cyclodextrin inclusion complexes demonstrate great potential against improvement of solubility, stability, dissolution rate, enhancement through biological membrane, etc. Furthermore, its safety profiles, via a variety of administration routes (oral, parenteral, transmucosal) are addressed. Finally, this paper is primarily focused on the findings related to the effects of cyclodextrins/anticancer drugs and cyclodextrins/prostaglandins delivery systems, and on the therapeutical potentiality of drugs.",
publisher = "Institut za onkologiju, Sremska Kamenica",
journal = "Archive of Oncology",
title = "Cyclodextrins: New materials for drug disposition",
volume = "6",
number = "3",
pages = "125-129",
url = "https://hdl.handle.net/21.15107/rcub_farfar_198"
}
Tasić, L., Milić, J.,& Stupar, M.. (1998). Cyclodextrins: New materials for drug disposition. in Archive of Oncology
Institut za onkologiju, Sremska Kamenica., 6(3), 125-129.
https://hdl.handle.net/21.15107/rcub_farfar_198
Tasić L, Milić J, Stupar M. Cyclodextrins: New materials for drug disposition. in Archive of Oncology. 1998;6(3):125-129.
https://hdl.handle.net/21.15107/rcub_farfar_198 .
Tasić, Ljiljana, Milić, Jela, Stupar, Mirjana, "Cyclodextrins: New materials for drug disposition" in Archive of Oncology, 6, no. 3 (1998):125-129,
https://hdl.handle.net/21.15107/rcub_farfar_198 .
