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Sensitivity and specificity of a quality of life questionnaire qualeffo-41

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Sensitivity_and_specificity_pub_2013.pdf (72.47Kb)
Authors
Tadić, Ivana
Vujasinović-Stupar, Nada
Tasić, Ljiljana
Stevanović, Dejan
Dimić, A.
Stamenković, Bojana
Stojanović, S.
Milenković, S.
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Abstract
OBJECTIVES: International Osteoporosis Foundation Quality of Life questionnaire (QUALEFFO-41) is the specific questionnaire for the postmenopausal women with osteoporosis and vertebral fractures. Reliability of the questionnaire could be confirmed by sensitivity and specificity. The objective of this stidy is to test the sensitivity and specificity of the QUALEFFO-41 questionnaire. METHODS: A case-control study was conducted during the period of June 2010 - October 2011 to test the main characteristics of the questionnaire. The study included 100 patients with osteoporosis (50 cases with vertebral fractures and 50 controls without fractures). The questionnaire EQ-5D (with direct-scoring) was used for comparison of the results with the QUALEFFO-41 (with reverse-scoring). The study was performed in two medical centers in Serbia. RESULTS: The results of the ROC curve analysis (between the case and control group of patients) indicated that the AUC ranges for all five dimensions... of the QUALEFFO-41 questionnaire and the total score were 0.62–0.69. The QUALEFFO-41 had a better prediction of the value of HRQOL of cases compared to the generic questionnaire EQ-5D (the AUC difference of the total scores was 0.099, p=0.013). Correlations between the total scores of the QUALEFFO-41 and the EQ-5D health state value, for both groups, were negative and statistically significant (r=-0.78, p<0.001 and r = -0.73, p<0.001, respectively). CONCLUSIONS: The QUALEFFO-41 has the ability to detect the patients with osteoporosis and vertebral fractures among the osteoporosis patients. This questionnaire is more specific for the osteoporosis patients with fractures in relation to the EQ-5D questionnaire.

Source:
Value in Health, 2013, 16, 3, A228-A228
Publisher:
  • Elsevier Inc.
Note:
  • ISPOR 18th Annual International Meeting Research Abstracts

DOI: 10.1016/j.jval.2013.03.1156

ISSN: 1098-3015

WoS: 000318916402133

[ Google Scholar ]
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/1985
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - CONF
AU  - Tadić, Ivana
AU  - Vujasinović-Stupar, Nada
AU  - Tasić, Ljiljana
AU  - Stevanović, Dejan
AU  - Dimić, A.
AU  - Stamenković, Bojana
AU  - Stojanović, S.
AU  - Milenković, S.
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1985
AB  - OBJECTIVES: International Osteoporosis Foundation Quality of Life questionnaire
(QUALEFFO-41) is the specific questionnaire for the postmenopausal women
with osteoporosis and vertebral fractures. Reliability of the questionnaire could
be confirmed by sensitivity and specificity. The objective of this stidy is to test
the sensitivity and specificity of the QUALEFFO-41 questionnaire. METHODS: A
case-control study was conducted during the period of June 2010 - October 2011
to test the main characteristics of the questionnaire. The study included 100
patients with osteoporosis (50 cases with vertebral fractures and 50 controls
without fractures). The questionnaire EQ-5D (with direct-scoring) was used for
comparison of the results with the QUALEFFO-41 (with reverse-scoring). The
study was performed in two medical centers in Serbia. RESULTS: The results of
the ROC curve analysis (between the case and control group of patients)
indicated that the AUC ranges for all five dimensions of the QUALEFFO-41
questionnaire and the total score were 0.62–0.69. The QUALEFFO-41 had a better
prediction of the value of HRQOL of cases compared to the generic questionnaire
EQ-5D (the AUC difference of the total scores was 0.099, p=0.013). Correlations
between the total scores of the QUALEFFO-41 and the EQ-5D health state value,
for both groups, were negative and statistically significant (r=-0.78, p<0.001 and r
= -0.73, p<0.001, respectively). CONCLUSIONS: The QUALEFFO-41 has the ability
to detect the patients with osteoporosis and vertebral fractures among the
osteoporosis patients. This questionnaire is more specific for the osteoporosis
patients with fractures in relation to the EQ-5D questionnaire.
PB  - Elsevier Inc.
C3  - Value in Health
T1  - Sensitivity and specificity of a quality of life questionnaire qualeffo-41
VL  - 16
IS  - 3
SP  - A228
EP  - A228
DO  - 10.1016/j.jval.2013.03.1156
ER  - 
@conference{
author = "Tadić, Ivana and Vujasinović-Stupar, Nada and Tasić, Ljiljana and Stevanović, Dejan and Dimić, A. and Stamenković, Bojana and Stojanović, S. and Milenković, S.",
year = "2013",
abstract = "OBJECTIVES: International Osteoporosis Foundation Quality of Life questionnaire
(QUALEFFO-41) is the specific questionnaire for the postmenopausal women
with osteoporosis and vertebral fractures. Reliability of the questionnaire could
be confirmed by sensitivity and specificity. The objective of this stidy is to test
the sensitivity and specificity of the QUALEFFO-41 questionnaire. METHODS: A
case-control study was conducted during the period of June 2010 - October 2011
to test the main characteristics of the questionnaire. The study included 100
patients with osteoporosis (50 cases with vertebral fractures and 50 controls
without fractures). The questionnaire EQ-5D (with direct-scoring) was used for
comparison of the results with the QUALEFFO-41 (with reverse-scoring). The
study was performed in two medical centers in Serbia. RESULTS: The results of
the ROC curve analysis (between the case and control group of patients)
indicated that the AUC ranges for all five dimensions of the QUALEFFO-41
questionnaire and the total score were 0.62–0.69. The QUALEFFO-41 had a better
prediction of the value of HRQOL of cases compared to the generic questionnaire
EQ-5D (the AUC difference of the total scores was 0.099, p=0.013). Correlations
between the total scores of the QUALEFFO-41 and the EQ-5D health state value,
for both groups, were negative and statistically significant (r=-0.78, p<0.001 and r
= -0.73, p<0.001, respectively). CONCLUSIONS: The QUALEFFO-41 has the ability
to detect the patients with osteoporosis and vertebral fractures among the
osteoporosis patients. This questionnaire is more specific for the osteoporosis
patients with fractures in relation to the EQ-5D questionnaire.",
publisher = "Elsevier Inc.",
journal = "Value in Health",
title = "Sensitivity and specificity of a quality of life questionnaire qualeffo-41",
volume = "16",
number = "3",
pages = "A228-A228",
doi = "10.1016/j.jval.2013.03.1156"
}
Tadić, I., Vujasinović-Stupar, N., Tasić, L., Stevanović, D., Dimić, A., Stamenković, B., Stojanović, S.,& Milenković, S.. (2013). Sensitivity and specificity of a quality of life questionnaire qualeffo-41. in Value in Health
Elsevier Inc.., 16(3), A228-A228.
https://doi.org/10.1016/j.jval.2013.03.1156
Tadić I, Vujasinović-Stupar N, Tasić L, Stevanović D, Dimić A, Stamenković B, Stojanović S, Milenković S. Sensitivity and specificity of a quality of life questionnaire qualeffo-41. in Value in Health. 2013;16(3):A228-A228.
doi:10.1016/j.jval.2013.03.1156 .
Tadić, Ivana, Vujasinović-Stupar, Nada, Tasić, Ljiljana, Stevanović, Dejan, Dimić, A., Stamenković, Bojana, Stojanović, S., Milenković, S., "Sensitivity and specificity of a quality of life questionnaire qualeffo-41" in Value in Health, 16, no. 3 (2013):A228-A228,
https://doi.org/10.1016/j.jval.2013.03.1156 . .

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