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Anatomical characterization, chemical analyses and essential oil antimicrobial activity of Hyssopus officinalis L. (Lamiaceae)
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2022)
Introduction
Hyssopus officinalis L. (Lamiaceae) is a perennial aromatic subshrub, distributed mainly in the Mediterranean area. The aerial parts of the plant are used as a culinary and medicinal herb (Hyssopi herba) ...
Applicability of Expert System for Drug Development as a tool for co-processed excipients formulation development
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Expert System for Drug Development, i.e. SeDeM
Expert System (Span. Sistema Experto para DEsarrollo
de Medicamentos) represents a method intended for
evaluation of powder properties affecting processability,
particularly ...
Pharmaceutical and technological characteristics of barium sulphate tablets -the screening of various formulation factors
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Introduction The study examined the development of barium sulphate tablets that do not dissolve in the digestive tract
and are used as a contrasting agent for measuring transit time through the column. The main problem ...
Selective laser sintering (SLS) 3D printing process: Influence of model design on the properties of zolpidem tartrate tablets
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Three-dimensional printing (3DP) is an innovative
additive manufacturing technology in the field of
pharmaceuticals that has the potential to provide small
batches of patient-tailored medicines (Wang et al., 2021).
One ...
Assessment of mucoadhesive buccal tablets with propranolol hydrochloride using principal component analysis
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Multivariate analysis methods are a set of statistical
techniques that allow multiple variables to be tested
simultaneously. This makes them ideal for studying
relationships in large complex datasets. Pharmaceutical
products ...
3D printing of carvedilol oral dosage forms using selective laser sintering technique
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
The adjustment of the dose according to the individual
needs of the patient is a unique advantage of 3D printing
technology, which is of particular importance for the
pediatric and geriatric population, due to the diverse ...
From co-processing by melt granulation towards direct compression of high ibuprofen loaded formulations
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Direct compression, as the simplest and therefore
preferable method of tableting, is often hindered by poor
flow and compaction properties of the active
pharmaceutical ingredient (API). Tableting by direct
compression ...
Selenium nanoparticles render pandrug-resistant Acinetobacter baumannii susceptible to colistin
(Macedonian Pharmaceutical Association, 2022)
Colistin is used as a “last resort” drug in the treatment
of carbapenem-resistant Acinetobacter baumannii
infections. Though not the most convenient option due to
the serious side effects, this antibiotic can be very ...
Fun-shaped oral dosage forms for the pediatric population fabricated by digital light processing (DLP) 3D printing technique
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2022)
Introduction Three-dimensional (3D) printing as an innovative technology in the field of drug manufacturing has attracted a lot of attention from the scientific and professional public in recent years. Classified into seven ...
Characterization of chitosan/xanthan gum polyelectrolyte complexes as carriers for ibuprofen: influence of drug encapsulation procedure on complex formation
(Macedonian Pharmaceutical AssociationFaculty of Pharmacy, Ss Cyril and Methodius University in Skopje, 2020)
Introduction
Ibuprofen (IBU) is commonly used non-steroidal
anti-inflammatory drug. It is a weak acid (pKa ~4.5)
with low pH dependent aqueous solubility (46
μg/mL at pH 1.5 and ˃300 μg/mL at pH˃7, at 25
°C). The most ...