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Clinical pharmacokinetic characteristics of novel antiepileptic drugs
(Nova Science Publishers, Inc., 2012)
The choice of an antiepileptic drug (AED) is usually based upon the epileptic seizure type. However, pharmacokinetic (PK) characteristics of AEDs may be valuable support in choosing the optimal therapeutic option for the ...
Objective skin performance evaluation: How mild are APGs to the skin?
(Elsevier Inc., 2014)
Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection ...
The Impact of Urea on the Colloidal Structure of Alkylpolyglucoside-Based Emulsions: Physicochemical and In Vitro In Vivo Characterization
(Wiley-VCH Verlag GMBH, Weinheim, 2011)
Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Robustness of liquid chromatographic method: How to achieve it and how to confirm it?
(Nova Science Publishers, Inc., 2013)
The quality of liquid chromatographic methods developed for pharmaceutical applications is strongly dependent on their robustness. The robustness issue requires a studious strategy where many important aspects regarding ...
Modified Natural Zeolites-Functional Characterization and Biomedical Application
(Wiley Blackwell, 2014)
Natural and synthetic zeolites have emerged as potential materials for biomedical application in recent years. Zeolites are hydrated microporous tektoaluminosilicates consisting of three-dimensional frameworks of SiO4 and ...
Chemometric methods application in pharmaceutical products processes analysis control
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on chemometrics and chemometric methods for the analysis of multivariate data. Multivariate data analysis is essential for both product and process development and ...
Quality-by-design in pharmaceutical development
(Elsevier Inc., 2013)
This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...