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Sinteza i antikancerski potencijal 4-azolilkumarina / Synthesis and anticancer potential of 4-azolylcoumarins
(Srpsko hemijsko društvo, Beograd, 2021)
Kumarini su heterociklična jedinjenja veoma rasprostranjen u prirodi. Kao privilegovana struktura,
ovaj molekul se nalazi i u velikom broju sintetskih derivata sa značajnom biološkom aktivnošću.
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DNA, protein and lipid oxidative damage in tissues of spontaneously hypertensive versus normotensive rats
(Elsevier Ltd, 2021)
Oxidative damage to protein and lipid macromolecules in target organs in hypertension has been recognized as a major factor contributing to cardiovascular, cerebrovascular, and renal diseases. Data on protein and lipid ...
Evaluation of potential of amino acids for amorphization and dissolution improvement of carvedilol
(International Association for Pharmaceutical Technology, Mainz, Germany, 2021)
INTRODUCTION
The development of formulations with amorphous form of drug is one of the most commonly used approaches for improving solubility and bioavailability of poorly soluble drugs. Solid dispersions with different ...
The novel approach towards gradient elution HPLC method development
(Ankara University Faculty of Pharmacy, 2021)
Introduction: Gradient elution HPLC finds its
purpose in simultaneous analyses of solutes
covering wide range of polarities. However, the
instrument related factors, especially dwell volume, are frequently responsible ...
Barks of Three Wild Pyrus Taxa: Phenolic Constituents, Antioxidant Activity, and in Vitro and in Silico Investigations of α-Amylase and α-Glucosidase Inhibition
(John Wiley and Sons Inc, 2021)
Dry MeOH extracts of the twig barks of Pyrus communis subsp. pyraster, P. spinosa and their hybrid P.×jordanovii nothosubsp. velenovskyi, collected in wild in Serbia, were analyzed. By LC/MS, the contents of arbutin ...
Pharmacy and nature ‐ plenty of diversity / Farmacija i priroda – bogatstvo diverziteta
(Savez farmaceutskih udruženja Srbije (SFUS), 2021)
In the most general sense, nature represents the unity of soil, water and air and all living beings. Man and all his activities affect life on our planet in different ways, often through gross violations of natural laws ...
In vitro and in silico investingation of antimicrobial activity of essential oils from two Pastinaca sativa subspecies
(University Prince of Songkla, ThailandUniversity of Novi Sad, Faculty of Sciences, Serbia, Novi Sad, 2021)
INTRODUCTION:
Cultivated parsnip (Pastinaca sativa subsp. sativa L., Apiaceae) root is a well-known vegetable, common ingredient of soups, stews, salads, casseroles etc. Besides, its leaves and young shoots can be added ...
Olive leaf, DNA damage and chelation therapy
(Elsevier, 2021)
Olive leaf (OL) is a precious source of bioactive compounds for versatile biomedical applications. Oleuropein, the main constituent from olive leaves, and its metabolite hydroxytyrosol are responsible for the majority of ...
Microenvironmental pH-modified solid dispersions for improving dissolution rate of valsartan
(International Association for Pharmaceutical Technology, Mainz, Germany, 2021)
INTRODUCTION
Formulation of solid dispersions (SDs) with water soluble polymers is one of the most efficient approaches for improving the dissolution rate of poorly soluble drugs. However, this formulation approach might ...
Quantitative Structure-Activity Relationships of xanthen-3-one and xanthen-1,8-dione derivatives and design of new compounds with enhanced antiproliferative activity on HeLa cervical cancer cells
(Taylor & Francis, 2021)
Xanthene derivatives have become a group of molecules of great importance in discovering of
new anticancer drugs. Recent studies of our group performed on xanthen-3-one and xanthen-
1,8-dione derivatives have shown their ...