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Predicting sulforaphane-induces adverse effects in prostatic cancer patients via in silico investigation
(Elsevier, 2023)
Prostate cancer is a major cause of death in men. Traditional therapies have limited efficacy, leading to the increased interest in phytochemicals like sulforaphane (SFN), found in cruciferous vegetables. ...
Comparative study of positive and negative sulforaphane activity against different tumor types via bioinformatic analysis
(Elsevier, 2023)
Sulforaphane (SFN) is a compound found in cruciferous vegetables which have been studied as a molecule with the potential in disease prevention and treatment. ...
Mechanistic studies of sulforaphane induced toxicity: in silico approach
(Elsevier B.V., 2022)
The effect of real-life toxic metal(oid)s mixture on the redox status in testicular tissues of rats
(Elsevier, 2023)
Infertility and other reproductive health issues have emerged as one of the world’s foremost challenges in recent decades. Globally, around 15% of couples suffer from infertility, and male partners are shown to be responsible ...
Metals in the Mix: Uncovering the Link Between Real-Life Environmental Exposures, Hormone Disruption, and Female Reproductive Health using Human and Animal Data
(Elsevier, 2023)
Toxic metal(oid)s are being frequently referred to as endocrine-disrupting chemicals (EDCs), and as they are prevalent in nature, they may be linked to the current reproductive issues confronting the female population. [1,2] ...
Oxidative damage in liver tissue induced by low doses exposure to a mixture of lead and polychlorinated biphenyls: Subacute toxicity study in rats
(Elsevier, 2023)
Considering that combined exposure to toxic metals and organic pollutants may induce various adverse effects on human health, it is important to elucidate the mechanisms of toxicity that occur after lowdose exposure to ...
Derivation of benchmark doses for male reproductive toxicity in a subacute low-level Pb exposure model in rats
(Elsevier Ireland Ltd, 2023)
The objectives of the study were to simulate low-level Pb exposure scenario in an animal model and to examine reproductive adverse effects. Based on obtained data, we have performed Benchmark dose (BMD)-response modelling. ...