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Development of level a in vitro - in vivo correlation for carbamazepine immediate release tablets
(Elsevier Science BV, 2005)
Predicting in vivo behavior of sustained release matrix tablet formulation: numerical convolution versus artificial neural network analysis
(Elsevier Science BV, Amsterdam, 2005)
Population pharmacokinetics of topiramate in adult patients with epilepsy using nonlinear mixed effects modelling
(Elsevier Science BV, Amsterdam, 2013)
The objective of the study was to develop population pharmacokinetic model of topiramate (TPM) using nonlinear mixed effects modelling approach. Data were collected from 78 adult epileptic patients on mono- or co-therapy ...
The influence of drug-drug interaction and patients' characteristics on valproic acid's clearance in adults with epilepsy using nonlinear mixed effects modeling
(Elsevier Science BV, Amsterdam, 2009)
Monitoring valproic acid (VPA) concentrations is especially challenging due to its highly variable pharmacokinetics (PK) and complex interactions with other antiepileptic drugs. We used sparse routine therapeutic drug ...
Application of dynamic neural networks in the modeling of drug release from polyethylene oxide matrix tablets
(Elsevier Science BV, Amsterdam, 2009)
The main objective of this study was to demonstrate the possible use of dynamic neural networks to model diclofenac sodium release from polyethylene oxide hydrophilic matrix tablets. High and low molecular weight polymers ...
The role of therapeutic drug monitoring in optimazing pharmacotherapy of selected antiepileptics
(Elsevier Science BV, Amsterdam, 2009)
A contribution to biopharmaceutical characterization of drug substances: cefaclor case
(Elsevier Science BV, Amsterdam, 2013)