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Current computer-aided drug design methodologies in discovery of novel drug candidates for neuropsychiatric and inflammatory diseases / Metode kompjuterski potpomognutog dizajniranja lekova u istraživanju novih potencijalnih terapeutika za neuropsihijatrijske i inflamatorne bolesti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Drug discovery and development is a very challenging, expensive and time-consuming
process. Impressive technological advances in computer sciences and molecular biology have
made it possible to use computer-aided drug ...
Multiparticulate oral formulations as a viable strategy for precise drug dosing in pediatrics: propranolol case study / Višečestične formulacije lekova za oralnu primenu kao strategija za precizno doziranje kod pedijatrijskih pacijenata - studija slučaja propranolola
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
The development of solid dosage forms that are both convenient for administration and allow precise drug dosing for pediatric patients is one of the great challenges in contemporary pharmaceutical technology. The presented ...
Experimental design in HPLC separation of pharmaceuticals / Primena eksperimentalnog dizajna za razdvajanje lekova HPLC metodom
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Design of Experiments (DoE) is an indispensable tool in contemporary drug analysis as it
simultaneously balances a number of chromatographic parameters to ensure optimal separation
in High Pressure Liquid Chromatography ...
Review of machine learning algorithms´ application in pharmaceutical technology / Pregled primene algoritama mašinskog učenja u farmaceutskoj tehnologiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Machine learning algorithms, and artificial intelligence in general, have a wide range of
applications in the field of pharmaceutical technology. Starting from the formulation
development, through a great potential for ...
A review of botanical characteristics, chemical composition, pharmacological activity and use of parsley / Pregled botaničkih karakteristika, hemijskog sastava, farmakološke aktivnosti i primene peršuna
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Parsley is a biennial aromatic plant from the Apiaceae family, which is characterized by an unbranched root, pinnately divided leaves, umbels and schizocarp. It contains essential oil in all parts, with phenylpropane and ...
Photocontrollable PROTAC molecules – structure and mechanism of action / Fotokontrolisani PROTAC molekuli - struktura i mehanizam dejstva
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Traditional drug discovery strategies are usually focused on occupancy of binding sites that directly affect functions of proteins. Hence, proteins that lack such binding sites are generally considered pharmacologically ...
Rheological behavior study and its significance in the assessment of application properties and physical stability of phytosome loaded hydrogels / Ispitivanje reološkog ponašanja i njegov značaj za procenu aplikativnih svojstava i fizičke stabilnosti hidrogelova sa fitosomima
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Phytosomes are amphiphilic molecular complexes of substances of plant origin and phospholipids that are considered as active ingredients of dermopharmaceutical and cosmetic formulations of potentially improved ...
The emerging role of physiologically-based pharmacokinetic/biopharmaceutics modeling in formulation development / Uloga fiziološki-zasnovanog farmakokinetičkog/biofarmaceutskog modelovanja u razvoju farmaceutskih preparata
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Computer-based (in silico) modeling & simulation tools have been embraced in different
fields of pharmaceutics for a variety of applications. Among these, physiologically-based
pharmacokinetic/biopharmaceutics modeling ...
Concept and utility of population pharmacokinetic and pharmacokinetic/ pharmacodynamic models in drug development and clinical practice / Koncept i upotreba populacionih farmakokinetičkih i farmakokinetičko/farmakodinamičkih modela u razvoju leka i kliničkoj praksi
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Due to frequent clinical trial failures and consequently fewer new drug approvals, the need
for improvement in drug development has, to a certain extent, been met using model-based drug
development. Pharmacometrics is a ...
Spectrophotometric determination of morin in strawberries and their antioxidant activity / Spektrofotometrijsko određivanje sadržaja morina u jagodama i njihove antioksidantne aktivnosti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Morin is one of the flavonoids with intensive antioxidant activity. With the aim to use its benefits on human health, there is an increasing trend to pay attention to its content in food or supplements. The simplicity ...