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Discovery of membrane permeability, pharmacokinetics properties and mechanism of action for analogs of ethylenediamine-n,n′-di-2-(3-cyclohexyl)propionic acid and 1,3-propandiamine-n,n′-di-2-(3-cyclohexyl)propionic acid with antiproliferative activity using In Vitro and In Silico Methods
(Springer Verlag, 2020)
In previously in vitro studies on different cell lines and in vivo on melanoma and 4T1 murine breast cancer and metastasis it was shown antiproliferative activity for ester derivatives of (S,S)-ethylenediamine-N,N′-di-2- ...
Bias in medical biochemistry- what laboratory professionals need to know?
(Beograd : JUSK - Jedinstveno Udruženje Srbije za Kvalitet, 2021)
In medical laboratories, bias presents quantitative expression of trueness, as
analytical performance characteristic that describes systematic errors. Despite bias evaluation
is an integral part of basic lessons of ...
Hematotoxicity of lead, cadmium, mercury and arsenic low dosed mixtures relevant to environmental exposure: the Adverse Outcome Pathway framewor
(Elsevier, 2023)
Prostate cancer is a major cause of death in men. Traditional therapies have limited efficacy, leading to the increased interest in phytochemicals like sulforaphane (SFN), found in cruciferous vegetables. ...
Inhaler technique training of community pharmacists and common errors
(European Respiratory Society, 2020)
Introduction: Pharmacists have a significant role in improving patient inhaler technique (HK. Reddel, et al. Eur Respir J 2008;32: 812; Alismail A, et al. Respir Care 2016;61:593). Hence, it is crucial for pharmacists to ...
Anticholinergic and sedative drug burden in elderly patients with cardiovascular diseases (oral presentation)
(Springer Nature, 2021)
Background Exposure to anticholinergic and sedative drugs have been associated with adverse health outcomes in the elderly population, which can be measured in an individual patient using Drug Burden Index (DBI). Higher ...
Neuropharmacokinetics: the secret life of - old and novel - psychopharmacological drugs
(International Association of Physical Chemists, 2023)
Neuro pharmacokinetics: the secret life of - old and novel - psychopharmacological drugs
Miroslav Savić
Department of Pharmacology, Faculty of Pharmacy, University of Belgrade, Serbia
In the 21st century, the pace of ...
Cellulose hydrocolloids in meat products: Current status and challenges in developing functional food
(IOP Publishing Ltd, 2021)
Due to the growing health problems associated with the increased intake of saturated and trans fats, and the unbalanced n-6/n-3 ratio in the diet, in recent years numerous studies have focused on finding adequate substitutes ...
Characterization of unknown degradant of ziprasidone with NMR spetroscopy
(Society of Physical Chemists of Serbia, 2022)
Ziprasidone (ZIP) is the second generation antipsychotic drug with unique G-protein-coupled
(GPCR) receptor binding profile. It is a highly lipophilic and unstable compound. Our group
developed and validated the single ...
Particle Deposition in Respiratory Tract: Where are the Limits?
(Springer, Cham, 2021)
In last two decades in silico biopharmaceutics modelling has become increasingly important in all stages of drug development. One of the widely used pharmacokinetic modelling software is Gastro Plus that, with its additional ...
Chemical composition, anti-inflammatory effect and antitumor activity of curly dock fruit (Rumex crispus L., Polygonaceae) / Hemijski sastav, antiinflamatorni efekat i antitumorska aktivnost ploda štavelja (Rumex crispus L., Polygonaceae)
(Savez farmaceutskih udruženja Srbije (SFUS), 2022)
Curly dock (Rumex crispus L.) is a perennial herbaceous plant that is traditionally used
in the treatment of gastrointestinal ailments, infections and skin diseases. The aim of this
study was to examine the chemical ...