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EDTA chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead / EDTA helatna terapija smanjuje oksidativno DNK oštećenje u limfocitima periferne krvi radnika profesionalno izloženih olovu
(Eko centar, centar za sociološka istraživanja i dokumentaciju, 2012)
INTRODUCTION: Pathogenetic effect of lead (Pb) is multifactorial and it is known that one of the ways which lead damages cellular components is by direct formation of reactive oxygen species. ...
DOLE protects leucocytes from hormone-induced DNA damage in vitro
(Serbian Genetic Society, Belgrade, 2014)
Both hormones thyroxin and adrenaline increase endogenous formation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage. Dry olive leaf extract (DOLE) is plant product known to modulate effects of ...
Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro
(International Comet Assay Working Group (ICAWG), 2019)
Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols ...
Unexpected effect of dry olive leaf extract (DOLE) before and after CaNa2EDTA chelation therapy in comet assay in lead intoxicated workers
(International Congress on Occupational & Environmental Toxicology - ICOETox 2016, 2016)
The CaNa2EDTA chelation is a standard therapy for lead (Pb) intoxication in occupationally exposed workers. Application of antioxidant nutrients through exogenous supplementation is often practiced with the chelation ...
Antigenotoxic effect of quercetin on thyroxine-induced DNA damage in human whole blood cells in vitro
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2019)
The binding of thyroid hormones to specific nuclear receptors in target cells induces synthesis of enzymes associated with redox processes, leading to the formation of reactive oxygen species (ROS), which can cause damage ...
Evaluation of the antioxidant potential of Biochaga in vitro
(Macedonian Academy of Sciences and Arts, 2023)
Background: Antioxidants and prooxidants have an impact on the intracellular oxidative equilibrium. Overproduction of prooxidants leads to oxidative stress caused by imbalances in oxidative reduction pathways. The body can ...
Salvianolic acid B reduces hydrogen peroxide induced DNA damage in human peripheral blood cells in vitro
(International Comet Assay Working Group (ICAWG), 2017)
Salvianolic acid B (Sal B) is a polyphenol compound derived from the Salvia miltiorrhiza plant which showed multitude of biological activities in vitro, including antioxidant, anti-inflammatory, cytotoxic and neuroprotective ...
Assessment of DNA damage in blood, liver and kidney cells in a hypertensive rat model using comet assay
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2019)
Hypertension is one of the primary risk factors for heart disease and stroke, the leading causes of death worldwide. Numerous factors have been implicated in the pathophysiology of hypertension: endothelial dysfunction, ...
Antigenotoxic effects of Biochaga and Dihydroquercetin (taxifolin) on H2O2 induced DNA damage in human WBC
(Turkish Society of Toxicology, 2019)
The health benefits of natural products have long been recognized. Consumption of dietary compounds such as supplements, provides an alternative source of natural products to those obtained from the diet. There is a growing ...