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dc.creatorRakić, Tijana
dc.creatorJančić-Stojanović, Biljana
dc.creatorJovanović, Marko
dc.creatorMalenović, Anđelija
dc.creatorIvanović, Darko
dc.creatorMedenica, Mirjana
dc.date.accessioned2019-09-02T11:36:38Z
dc.date.available2019-09-02T11:36:38Z
dc.date.issued2013
dc.identifier.issn0003-2719
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2003
dc.description.abstractThis paper investigates the ability of seven chromatographic response functions to measure the quality of chromatograms obtained in hydrophilic interaction liquid chromatography (HILIC). First, the functions were tested on a set of simulated chromatograms and differences in their mathematical design were discussed. Second, the functions were evaluated on the experimentally obtained chromatograms in HILIC analysis of model mixture consisted of beta agonists and antagonists. The ranking of chromatograms obtained by different functions was significantly different, implying that the accuracy of the optimization procedure is strongly dependent on the function that was selected as an output. Investigation of potential drawbacks of each function was conducted and general recommendations concerning the use of chromatographic response functions in optimization strategies are proposed.en
dc.publisherTaylor & Francis Inc, Philadelphia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172052/RS//
dc.rightsrestrictedAccess
dc.sourceAnalytical Letters
dc.subjectBeta agonists and antagonistsen
dc.subjectChromatographic response function (CRF)en
dc.subjectHILICen
dc.titleEvaluation of Seven Chromatographic Response Functions on Simulated and Experimentally Obtained Chromatograms in Hydrophilic Interaction Liquid Chromatography Systemen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractРакић, Тијана; Јовановић, Марко; Ивановић, Дарко; Меденица, Мирјана; Маленовић, Aнђелија; Јанчић-Стојановић, Биљана;
dc.citation.volume46
dc.citation.issue8
dc.citation.spage1198
dc.citation.epage1212
dc.citation.other46(8): 1198-1212
dc.citation.rankM23
dc.description.otherPeer-reviewed manuscript: [http://farfar.pharmacy.bg.ac.rs/handle/123456789/3419]
dc.identifier.wos000318281700002
dc.identifier.doi10.1080/00032719.2012.755689
dc.identifier.scopus2-s2.0-84877274218
dc.type.versionpublishedVersion


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