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dc.creatorGrbić, Sandra
dc.creatorParojčić, Jelena
dc.creatorĐurić, Zorica
dc.date.accessioned2019-09-02T11:37:04Z
dc.date.available2019-09-02T11:37:04Z
dc.date.issued2013
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2022
dc.description.abstractThis chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input parameters are described. Virtual trials for in silico modeling of drug absorption are presented. The influence of food on drug absorption, as well as correlation between the in vitro and in vivo results, are also addressed, followed by biowaiver considerations. Numerous examples are provided throughout the chapter.en
dc.publisherElsevier Inc.
dc.rightsrestrictedAccess
dc.sourceComputer-Aided Applications in Pharmaceutical Technology
dc.subjectBiowaiveren
dc.subjectFood effectsen
dc.subjectGastrointestinal absorptionen
dc.subjectIn silico modelingen
dc.subjectIn vitro-in vivo correlationen
dc.subjectParameter sensitivity analysisen
dc.subjectVirtual trialsen
dc.titleComputer-aided biopharmaceutical characterization: Gastrointestinal absorption simulationen
dc.typebookPart
dc.rights.licenseARR
dcterms.abstractГрбић, Сандра; Паројчић, Јелена; Ђурић, Зорица;
dc.citation.spage177
dc.citation.epage232
dc.citation.other: 177-232
dc.identifier.doi10.1016/B978-1-907568-27-5.50006-8
dc.identifier.scopus2-s2.0-84904142707
dc.identifier.rcubconv_4819
dc.type.versionpublishedVersion


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