Приказ основних података о документу

dc.creatorAgbaba, Danica
dc.creatorErić-Jovanović, S
dc.creatorŽivanov-Stakić, Dobrila
dc.creatorVladimirov, S
dc.date.accessioned2019-09-02T10:51:01Z
dc.date.available2019-09-02T10:51:01Z
dc.date.issued1998
dc.identifier.issn0047-2166
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/202
dc.description.abstractThe objective of this investigation was to develop an HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice. High performance thin-layer chromatography of cephalosporins was performed on pre-coated silica gel HPTLC plates with concentration zones (2.5×10cm), development with mobile phase ethylacetate-acetone-methanol-water (5:2.5:2.5:1.5 v/v). A TLC scanner (Camag, Muttenz, Switzerland) set at 270 nm was used for direct evaluation of the chromatograms in reflectance/absorbance mode. The calibration curves were established dependant of peak height (linear and polinomial regression) and peak area (polinomial regression) vs ng level (125-500 ng for all cephalosporins investigated). Coefficients of variation obtained from calibration curves were compared. Precision (c.v.: 1.12-2.91% (peak height vs ng) and c.v.: 1.05-2.75% (peak area vs ng)), and detection limits (ng level) were found to be satisfactory. The method is reproducible and convenient for quantitative analysis of ceftriaxone, cefixime and cefotaxime raw materials and their different dosage forms.en
dc.publisherAPB Algemene Pharmaceutische Bond
dc.rightsrestrictedAccess
dc.sourceJournal de Pharmacie de Belgique
dc.titleHPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage formsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЖиванов-Стакић, Добрила; Aгбаба, Даница; Ерић-Јовановић, С; Владимиров, С;
dc.citation.volume53
dc.citation.issue3
dc.citation.spage150
dc.citation.other53(3): 150-
dc.identifier.scopus2-s2.0-33750157551
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_202
dc.type.versionpublishedVersion


Документи

ДатотекеВеличинаФорматПреглед

Уз овај запис нема датотека.

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу