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Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets
dc.creator | Vujić, Zorica | |
dc.creator | Radulović, Dušanka | |
dc.date.accessioned | 2019-09-02T10:51:05Z | |
dc.date.available | 2019-09-02T10:51:05Z | |
dc.date.issued | 1998 | |
dc.identifier.issn | 1460-8081 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/203 | |
dc.description.abstract | Spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablet formulations were compared. Celiprolol hydrochloride and benzylorange react in a 1:1 ratio in the presence of phosphate buffer, producing a yellow, chloroform-extractable ion pair with an absorption maximum at 401 nm. The conditional stability constants were determined by Sommer and Job's method of non-equimolar solutions. The repeatability of the method was tested by analysing Selectol tablets. Spectrophotometric results were compared with those obtained UV-densitometrically on Silica Gel GF 254 plates with acetone-methanol-triethylamine as mobile phase. There was no significant difference in accuracy between the two methods, however the densitometric method was more rapid. | en |
dc.publisher | Wiley | |
dc.rights | restrictedAccess | |
dc.source | Pharmacy and Pharmacology Communications | |
dc.title | Comparison of spectrophotometric and UV-densitometric methods for the determination of celiprolol hydrochloride in tablets | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Вујић, Зорица; Радуловић, Душанка; | |
dc.citation.volume | 4 | |
dc.citation.issue | 10 | |
dc.citation.spage | 469 | |
dc.citation.epage | 471 | |
dc.citation.other | 4(10): 469-471 | |
dc.identifier.doi | https://doi.org/10.1111/j.2042-7158.1998.tb00655.x | |
dc.identifier.scopus | 2-s2.0-0031734647 | |
dc.type.version | publishedVersion |