Приказ основних података о документу

dc.creatorŽivković, Lada
dc.creatorBajić, Vladan
dc.creatorŽukovec, Dijana
dc.creatorČabarkapa, Andrea
dc.creatorPotparević, Biljana
dc.date.accessioned2019-09-02T11:38:01Z
dc.date.available2019-09-02T11:38:01Z
dc.date.issued2013
dc.identifier.issn0354-4664
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2060
dc.description.abstractWhile Alzheimer's disease (AD) is primarily considered to be a neurodegenerative disorder, there is much evidence supporting the idea that it is also a systematic disease, so the occurrence of genomic instability in cells that are not neurons is equally important. Accordingly, acrocentric chromosomes play an important role in the etiology of AD, especially the presence of trisomy 21. The aim of this work was to assess the relationship between the frequency of acrocentrics included in satellite association (SA) and acrocentrics with premature centromere division (PCD) in the peripheral blood lymphocytes of AD patients and age-matched controls. Since our results showed that there are significant differences in SA frequency, as well as in the frequency of PCD in acrocentrics between AD patients and control group, we may conclude that the occurrence of acrocentric chromosome alterations presented in this study could be related to the etiology of AD.en
dc.publisherSrpsko biološko društvo, Beograd, i dr.
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173034/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceArchives of Biological Sciences
dc.subjectSatellite associationen
dc.subjectpremature centromere divisionen
dc.subjectAlzheimer's diseaseen
dc.titleAlterations of acrocentric chromosomes in peripheral blood lymphocytes in patients with Alzheimer's diseaseen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractЖивковић, Лада; Бајић, Владан; Жуковец, Дијана; Чабаркапа, Aндреа; Потпаревић, Биљана;
dc.citation.volume65
dc.citation.issue2
dc.citation.spage439
dc.citation.epage445
dc.citation.other65(2): 439-445
dc.citation.rankM23
dc.identifier.wos000318826000004
dc.identifier.doi10.2298/ABS1302439Z
dc.identifier.scopus2-s2.0-84876976357
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/804/2058.pdf
dc.type.versionpublishedVersion


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Приказ основних података о документу